Results 51 to 60 of about 42,379 (316)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Explosive full-field strain and crack dynamic fracture characteristics of a linear shaped charge
工程科学学报, 2022 This study explores the full-field strain and dynamic fracture characteristics of a linear shaped charge under different initiation positions. The explosion dynamic caustic line experiment system is employed to examine the characteristics of the blast ...
Jin-jing ZUO +4 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Fatigue crack growth in thin notched woven glass composites under tensile loading. Part I: experimental [PDF]
, 2011 Helicopter blades are made of composite materials mainly loaded in fatigue and have normally relatively thin skins. A through-the-thickness crack could appear in these skins.
Barrau, Jean-Jacques +7 more
core +1 more source
Initiation of internal fatigue crack in a carbide-free bainitic steel during high cycle fatigue
Journal of Materials Research and TechnologyThe crack initiation stage is crucial to the overall fatigue behavior of the carbide-free bainitic steels. Through S–N curve testing and fracture observation, it is demonstrated that internal crack initiation is the dominant mode during high cycle ...
Bo Mi +5 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Jixie qiangdu, 2020 The fatigue crack initiation of the fuselage structure skin under the uniform supercharged cyclic load of 0 ～ 7. 8 Psi was experimentally studied by the self-made aircraft fuselage skin uniform supercharged fatigue simulation device.
LIU LiPing +5 more
doaj
Metals, 2022 The impact toughness of a high-strength metastable β titanium alloy (Ti-5Cr-4Al-4Zr-3Mo-2W-0.8Fe) with two typical microstructures is studied by Charpy impact tests. The bimodal microstructure (BM) and the lamellar microstructure (LM) are obtained by the
Jing Wang +5 more
doaj +1 more source
Crack initiation criteria in fretting fatigue
Wear, 1990 Abstract This paper is a description of a series of fretting fatigue tests on an Al/Cu alloy in which the contact size was varied while the other relevant parameters were held constant. The fretting fatigue life was found to be infinite below a certain critical contact width.
Nowell, D, Hills, D
openaire +1 more source