Results 101 to 110 of about 66,884 (287)

Numerical Strip-Yield Calculation of CTOD and CTOA [PDF]

open access: yes
A recently developed numerical method based on the strip yield analysis approach was used to calculate the Crack Tip Opening Displacement (CTOD) and Crack Tip Opening Angle (CTOA) for a number of complex crack configurations of practical interest.
Beek, Joachim   +2 more
core   +1 more source

Time–Harmonic Behaviour of a Cracked Piezoelectric Solid by BIEM [PDF]

open access: yes, 2012
ACM Computing Classification System (1998): J.2, G.1.9Time–harmonic behaviour of a cracked piezoelectric finite solid is studied by nonhypersingular traction Boundary Integral Equation Method (BIEM).
Marinov, Marin, Rangelov, Tsviatko
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Deformation mechanics of deep surface flaw cracks [PDF]

open access: yes
A combined analytical and experimental program was conducted to determine the deformation characteristics of deep surface cracks in Mode I loading. An approximate plane finite element analysis was performed to make a parameter study on the influence of ...
Beissner, R. E.   +2 more
core   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Finite-element analyses and fracture simulation in thin-sheet aluminum alloy [PDF]

open access: yes
A two-dimensional, elastic-plastic finite-element analysis was used with a critical crack-tip-opening angle (CTOA) fracture criterion to model stable crack growth in thin-sheet 2024-T3 aluminum alloy under monotonic loading after precracking at different
Bigelow, C. A.   +2 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Assessment of the interaction between three collinear unequal straightcracks with unified yield zones

open access: yesAIMS Materials Science, 2017
The Dugdale model has been modified in the paper to include the e ect of linearly varying yield stress distribution. An isotropic infinite plate is considered with three collinear unequal straight cracks with coalesced yield zones.
doaj   +1 more source

Experimental and analytical study of cracks under biaxial fatigue [PDF]

open access: yes, 2016
Most mechanical components experience multi-axial cyclic loading conditions during service. Experimental analysis of fatigue cracks under such conditions is not easy and most works tend to focus more on the simpler but less realistic case of uni-axial ...
Camas, Daniel   +5 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy