Results 81 to 90 of about 8,141 (305)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Propagation of cohesive crack in unsaturated porous media by use of XFEM method
E3S Web of Conferences, 2016 Various damage models have been presented to model the cracks. These models don’t simulate the discontinuity in displacement field; just see its effect on an upper level on stress field through damage parameter.
Mokhtari Alireza +2 more
doaj +1 more source
Some experimental observations of crack-tip mechanics with displacement data [PDF]
, 2015 Estudio de la mecánica en el vértice de la grieta mediante datos de desplazamiento.In the past two decades, crack-tip mechanics has been increasingly studied with full-field techniques.
Moreno-Morales, María Belén +12 more
core +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
SIMULATION STUDY ON OPENING MECHANISM OF THERMALMECHANICAL CRACK OF BRAKE DISC
Jixie qiangdu, 2017 Considering physical properties variation of gray cast iron with temperature,difference mechanical behavior of material between compression and tension,relationship of elastic and plastic stress-strain of material,synthetically studied the temperature ...
NI Jing +3 more
doaj
Cyclic J integral using linear matching method
, 2012 The extended version of the latest Linear Matching Method (LMM) has the capability to evaluate the stable cyclic response, which produces cyclic stresses, residual stresses and plastic strain ranges for the low cycle fatigue assessment with cyclic load ...
Chen, Haofeng, Chen, Weihang
core
In-situ observation of crack opening displacement (COD) in a metastable beta titanium composite
, 2008 The interfacial strength of beta-Ti composites was increased via ageing, to investigate the effects of interfacial strength on the crack opening. Prior to crack opening displacement (COD) measurements, the number and location of fractured fibres were ...
Bowen, Paul +4 more
core +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Measurement of Crack Tip Opening Displacement of Paper Using CCD Camera
, 1999 Crack opening displacement (COD) on a deep double notched tension specimen was quantitatively analyzed and showed a linear relationship between COD and the distance from the crack tip all through the testing period.
Tanaka, Atsushi; id_orcid +1 more
core