Results 71 to 80 of about 8,141 (305)

Effect of hydration and crack orientation on crack-tip strain, crack opening displacement and crack-tip shielding in elephant dentin [PDF]

open access: yes, 2018
Objectives. To quantify the extent of crack-tip plasticity, crack opening displacement (COD) and crack bridging for crack growth perpendicular (HAH) and parallel (RAR) to the tubules in elephant dentin under both hydrated and dry conditions to better ...
Rawson, Shelley   +8 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Determination of fracture mechanics parameters by digital image correlation method of surface crack for 7075 Al alloy under nonproportional cyclic loading (Growth life prediction method considering shear stress on the crack surface)

open access: yesNihon Kikai Gakkai ronbunshu
A method for predicting the propagation life of a crack initiated on the surface of a 7075 aluminum alloy under nonproportional loading was proposed using the modified Paris law.
Yuichi ONO, Kaito WATANABE, Nao KANEKO
doaj   +1 more source

Analysis influence of Dmax on fracture mechanics parameters of concrete made of limestone aggregate at three point bending.

open access: yesBudownictwo i Architektura, 2007
The analysis of concrete behaviour taking into account fracture mechanics method makes it possible to describe the origin and development of the damages occurring in it, which is impossible in case of using global strength characteristics of composite ...
Grzegorz Golewski
doaj   +1 more source

Numerical Analysis of the Influence of In-Plane Constraints on the Crack Tip Opening Displacement for SEN(B) Specimens Under Predominantly Plane Strain Conditions

open access: yes, 2016
This paper presents a numerical analysis of the relationship between in-plane constraints and the crack tip opening displacement (CTOD) for single-edge notched bend (SEN(B)) specimens under predominantly plane strain conditions.
M. Graba, Graba, M.
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Plasticity and the crack opening displacement in shells

open access: yes, 1970
Plastic deformation and crack opening displacement in thin walled, cylindrical ...
Erdogan, F., Ratwani, M.
core  

Method of Obtaining Dynamic Stress Intensity Factor by Measuring Crack Mouth Opening Displacement on a 3-Point Bending Specimen

open access: yes, 2012
This paper focuses on how to obtain the Dynamic Stress Intensity Factor by measuring Crack Mouth Opening Displacement on a pre-cracked 3-Point Bending Specimen.
Huang, Yayu   +7 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Digital image correlation method in experimental analysis of fracture mechanics parameters [PDF]

open access: yesScientific Technical Review, 2017
The principles and examples of state-of-the-art experimental methods for measuring the fracture mechanics parameters are presented in this paper. The methodology of experimental analysis of the fracture mechanics parameters includes investigation of ...
Čolić Katarina   +4 more
doaj  

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