Results 41 to 50 of about 210,549 (294)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Quasistatic crack evolution for a cohesive zone model with different response to loading and unloading: a Young measures approach [PDF]

, 2009
A new approach to irreversible quasistatic fracture growth is given, by means of Young measures. The study concerns a cohesive zone model with prescribed crack path, when the material gives different responses to loading and unloading phases.
Barenblatt, Cagnetti, Dal Maso, Dal Maso, Dal Maso, Filippo Cagnetti, Francfort, Rodica Toader   +7 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Assessment of 3D Short Crack Closure in Ti-6Al-4V Alloy Utilizing Synchrotron X-ray Microtomography [PDF]

MATEC Web of Conferences, 2020
Synchrotron X-ray microtomography was utilized to observe the complex 3D crack morphology and the closure behavior of a short crack in Ti-6Al-4V alloy. The aim of the study was to investigate the effect of the crack path evolution on the 3D short crack ...
TUBEI Valary, HASSANIPOUR Meysam, HIRAYAMA Kyosuke, TODA Hiroyuki, TAKEUCHI Akihisa, UESUGI Kentaro   +5 more
doaj   +1 more source

Fatigue crack propagation behaviour in wire+arc additive manufactured Ti‐6Al‐4V: Effects of microstructure and residual stress [PDF]

, 2016
Fatigue crack propagation tests of Ti‐6Al‐4V fabricated by the Wire+Arc Additive Manufacturing (WAAM) process are analysed. Crack growth rate and trajectory are examined before and after the crack tip crossing an interface between the WAAM and wrought ...
ABAQUS 6.13, Addison, Almeida, Antonysamy, Antonysamy, ASTM E647-13, Baufeld, Baufeld, Baufeld, Brandl, Che-Haron, Cheng, Colegrove, Dattoma, Ding, Edwards, Edwards, Ezugwu, Frazier, Gurney, Hills, Hosseinzadeh, Kelly, Kelly, Li, Liu, Lorant, Lutjering, Martina, Paradowska, Prime, Prime, Prime, Rangaswamy, Schroeder, Shiomi, Taminger, Wang, Wang, Wang, Zhang   +40 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Fracture Characteristics of 3D-Printed Polymer Parts: Role of Manufacturing Process

Journal of Manufacturing and Materials Processing
Using traditional methods to fabricate geometrically complicated items was challenging, but Additive Manufacturing (AM) has made it possible. Although AM (3D printing) was first developed to produce prototypes, in recent years it has also been utilized ...
Mohammad Reza Khosravani, Payam Soltani, Majid R. Ayatollahi, Tamara Reinicke   +3 more
doaj   +1 more source

Fatigue Crack Propagation Path and Life Prediction Based on XFEM

Xibei Gongye Daxue Xuebao, 2019
Based on the theory of linear elastic fracture mechanics, the relationships between material constants c3, c4 required in Abaqus and constants C, m in Paris formula are derived.

doaj   +1 more source

A finite element strategy coupling a gradient-enhanced damage model and cohesive cracks for quasi-brittle materials [PDF]

, 2013
A new combined strategy to describe failure of quasi-brittle materials is presented thus allowing the complete description of the process, from initiation of damage to crack propagation.
Rodríguez Ferran, Antonio, Tamayo-Mas, Elena   +1 more
core  

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source