Results 51 to 60 of about 2,962 (211)
Jixie qiangdu, 2015 In this article,elastic-plastic curved crack tip plasticity area in hardened material under quasi-static loads has been mainly studied,and curved crack tip plasticity area has been calculated as a practical application of a second order perturbation ...
YANG DaPeng, WANG JianXun, ZHAO Yao
doaj
Journal of Materials Research and TechnologyThe plastic deformation, crack initiation, crack propagation behaviors of M2 high speed steel were investigated by means of in-situ SEM observation during tensile.
Lihui Zhu +3 more
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
An Improved Method for Hull Structure Fatigue Crack Growth at Random Loading and Its Application
Journal of Marine Science and EngineeringUnder random wave loading, the crack growth rate exhibits jump-like cycle-to-cycle variations, which limit the direct use of efficient integration schemes such as the Euler method.
Ming Zhang +3 more
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2017 The initiation and growth of internal small fatigue cracks with around ten or several dozen μm in Ti-6Al-4V were nondestructively examined by using synchrotron radiation μCT at the large synchrotron radiation facility SPring-8.
Fumiyoshi YOSHINAKA +5 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Research on J integral of Crack Tip on Intersecting Line of Fracturing Pump Head
Shiyou jixie, 2018 To address the primary failure modes of the fracturing pump head, a finite element model with different angular crack size is established. The J integral of the crack front and the plastic zone size of the crack tip are calculated.
Wei Chao, Zhou Sizhu, Hua Jian, Zhang Si
doaj
Ultrasonic Sizing of Cracks in Web Geometries
, 1984 Evaluation of the critical nature of interior cracks in turbine rotor component web regions in order to assess the remaining service life of the parts requires accurate determination of the crack sizes in order to perform fracture mechanics analysis. This analysis is important both in order to retire critically defective parts and in order to return ...
Gray, Timothy, Thompson, R.Bruce
openaire +3 more sources
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source