Results 61 to 70 of about 396,290 (347)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Jixie qiangdu, 2018 In this article,three dimensional elastic-plastic curved crack tip plasticity area under quasi-static loads has been mainly studied,and three dimensional curved crack tip plasticity area has been calculated as a practical application of a second order ...
YANG DaPeng +3 more
doaj
Atomistic Representation of Anomalies in the Failure Behaviour of Nanocrystalline Silicene
, 2017 Silicene, a 2D analogue of graphene, has spurred a tremendous research interest in the scientific community for its unique properties essential for next generation electronic devices. In this work, for the first time, we present a molecular dynamics (MD)
Islam, Md Mahbubul +4 more
core +2 more sources
Local waiting time fluctuations along a randomly pinned crack front [PDF]
, 2005 The propagation of an interfacial crack along a heterogeneous weak plane of a transparent Plexiglas block is followed using a high resolution fast camera.
Måløy, Knut Jørgen +3 more
core +3 more sources
Influence of grain size and grain boundary misorientation on the fatigue\n crack initiation mechanisms of textured AZ31 Mg alloy [PDF]
, 2021 Abbas Jamali, Anxin Ma, Javier LLorca
openalex +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Mechanism of crack branching in the fatigue crack growth path of 2324-T39 Aluminium alloy
Fracture and Structural Integrity, 2015 The crack growth behavior in 2324-T39 aluminium alloy was experimentally investigated. Two types of crack branching were observed. The mechanism of an uncommon crack branching which results from the link up of secondary crack with the main crack was ...
Lu Songsong +3 more
doaj
Fracture behaviors of pre-cracked monolayer molybdenum disulfide: A molecular dynamics study
Beilstein Journal of Nanotechnology, 2016 The fracture strength and crack propagation of monolayer molybdenum disulfide (MoS2) sheets with various pre-existing cracks are investigated using molecular dynamics simulation (MDS).
Qi-lin Xiong +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Journal of Materials Research and TechnologyThe plastic deformation, crack initiation, crack propagation behaviors of M2 high speed steel were investigated by means of in-situ SEM observation during tensile.
Lihui Zhu +3 more
doaj +1 more source