Results 31 to 40 of about 68,059 (240)

BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development. [PDF]

open access: yesPLoS Genetics, 2018
Craniofacial abnormalities, including facial skeletal defects, comprise approximately one-third of all birth defects in humans. Since most bones in the face derive from cranial neural crest cells (CNCCs), which are multipotent stem cells, craniofacial ...
Kohei Kitami   +4 more
doaj   +1 more source

Distinct and redundant roles for zebrafish her genes during mineralization and craniofacial patterning

open access: yesFrontiers in Endocrinology, 2022
The Notch pathway is a cell-cell communication system which is critical for many developmental processes, including craniofacial development. Notch receptor activation induces expression of several well-known canonical targets including those encoded by ...
Amanda Stenzel   +6 more
doaj   +1 more source

A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development

open access: yesNature Communications, 2023
The molecular mechanisms that coordinate patterning of the embryonic ectoderm into spatially distinct lineages to form the nervous system, epidermis, and neural crest-derived craniofacial structures are unclear.
Anthony J. Asmar   +13 more
doaj   +1 more source

Craniofacial photographic superimposition: New developments

open access: yesForensic Science International: Synergy, 2019
Craniofacial superimposition is a technique used in the field of forensic anthropology to assist in the analysis of an unknown skull. The process involves superimposing an image of the recovered skull over an ante mortem image of the suspected individual.
Douglas H. Ubelaker   +2 more
openaire   +3 more sources

BMP signalling in craniofacial development

open access: yesThe International Journal of Developmental Biology, 2006
The BMP signalling pathway is conserved throughout evolution and essential for mammalian embryonic and postnatal development and growth. In the vertebrate head, this signal is involved in the development of a variety of structures and shows divergent roles.
Xuguang, Nie   +2 more
openaire   +3 more sources

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

open access: yesAdvanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv   +10 more
wiley   +1 more source

Shape‐Morphing Nanoengineered Hydrogel Ribbons as Hemostats

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces a self‐assembling, shape‐morphing nanoengineered hydrogel ribbon system that rapidly forms porous aggregates in situ for efficient hemostasis in trauma and surgical applications. Abstract Rapid and effective hemorrhage control remains a major challenge in trauma and surgical care, particularly for complex or noncompressible wounds.
Ryan Davis Jr   +9 more
wiley   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

open access: yesAdvanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello   +2 more
wiley   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum   +5 more
wiley   +1 more source

Distinct Embryonic Origin and Injury Response of Resident Stem Cells in Craniofacial Muscles

open access: yesFrontiers in Physiology, 2021
Craniofacial muscles emerge as a developmental novelty during the evolution from invertebrates to vertebrates, facilitating diversified modes of predation, feeding and communication.
Xu Cheng, Bing Shi, Jingtao Li
doaj   +1 more source

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