Results 31 to 40 of about 370,481 (201)

Increasing genomic instability during cancer therapy in a patient with Li-Fraumeni syndrome

open access: yesClinical and Translational Radiation Oncology, 2017
Background: Li-Fraumeni syndrome (LFS) is a cancer predisposition disorder characterized by germline mutations of the p53 tumor-suppressor gene. In response to DNA damage, p53 stimulates protective cellular processes including cell-cycle arrest and ...
Nadine Schuler   +4 more
doaj   +1 more source

Risk factors for cardiovascular diseases in patients received complex treatment for cranial and craniospinal tumors in childhood

open access: yesРоссийский кардиологический журнал, 2022
Aim. To study the traditional risk factors for cardiovascular disease (CVD), indicators of endothelial function and exercise tolerance in patients received complex treatment for cranial and craniospinal tumors in childhood, including radiation therapy ...
A. I. Novikova   +12 more
doaj   +1 more source

Proton craniospinal irradiation with bevacizumab and pembrolizumab for leptomeningeal disease: a case report. [PDF]

open access: yesCNS Oncol, 2023
Leptomeningeal disease (LMD) remains a challenging condition with a dismal prognosis. In this case study, we report partial response of LMD in a patient with metastatic large cell neuroendocrine carcinoma following treatment with proton craniospinal ...
Webb MJ   +5 more
europepmc   +2 more sources

Effective Radiotherapy Cured Cauda Equina Syndrome Caused by Remitted Intracranial Germinoma Depositing

open access: yesPediatrics and Neonatology, 2012
Cauda equina syndrome (CES) in children is very rare and can permanently disable. A remitted intracranial germinoma depositing on the spinal cord, leading to CES, has never been reported.
Ying-Chun Lu   +6 more
doaj   +1 more source

Optimizing Management of the Central Nervous System in Patients with Acute Lymphoblastic Leukemia Undergoing Allogeneic Stem Cell Transplantation

open access: yesAdvances in Radiation Oncology, 2023
Purpose: To evaluate clinical outcomes and patterns of failure, specifically in regards to the central nervous system (CNS), in patients with acute lymphoblastic leukemia (ALL) undergoing allogeneic hematopoietic stem cell transplantation (HSCT) using ...
Pranalee Patel, BS   +4 more
doaj   +1 more source

Seminoma with Neoplastic Meningitis Treated with Craniospinal Irradiation [PDF]

open access: yesThe Oncologist, 2018
Abstract Pure seminoma is a histological subtype of testicular cancer that accounts for 50% of testicular germ cell tumors. It has a very low rate of metastasis to the central nervous system, with only one previously reported case of neoplastic meningitis (cancer that has spread to the cerebrospinal fluid).
Kaylyn D, Sinicrope   +2 more
openaire   +2 more sources

Scoliosis in Children Treated With Photon Craniospinal Irradiation for Medulloblastoma [PDF]

open access: yesInternational Journal of Radiation Oncology*Biology*Physics, 2021
Scoliosis is a well-recognized complication after abdominal radiation therapy but not reported frequently after craniospinal irradiation (CSI). We examined the incidence and risk factors for scoliosis after CSI in long-term survivors with medulloblastoma.The records of patients with medulloblastoma seen at one institution from 1996 to 2006 were ...
Arnold C, Paulino   +5 more
openaire   +2 more sources

Craniospinal versus whole brain irradiation in Medulloblastoma patients, with introduction of utilizing a simple immobilization device [PDF]

open access: yesActa Medica Iranica, 2001
Craniospinal irradiation plus posterior fossa boost (CS1) is the standard modality of post-operative treatment of patient with medulloblastoma, but considering the technical difficulties and limited facilities, often whole- brain irradiation plus ...
Haddad P   +3 more
doaj   +2 more sources

Choroid plexus carcinoma with leptomeningeal spread in an adult: a case report and  review of the literature

open access: yesJournal of Medical Case Reports, 2021
Background Choroid plexus carcinoma is an intraventricular neoplasm originating from the choroid plexus epithelium and is of rare occurrence in adults.
In Young Jo   +3 more
doaj   +1 more source

Neurocognitive Deficits in Medulloblastoma Patients

open access: yesPediatric Neurology Briefs, 1999
Eighteen children previously treated surgically and with craniospinal irradiation for medulloblastoma (MED), and matched with a group having low-grade posterior fossa tumors with surgery alone, received neuropsychological testing and quantitative ...
J Gordon Millichap
doaj   +1 more source

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