MSC Membrane‐Coated circPROSC‐siRNA Nanoparticles for Ameliorating Craniosynostosis by Inhibiting Premature Suture Ossification [PDF]
Advanced ScienceCraniosynostosis is a congenital craniofacial disorder caused by excessive osteogenic differentiation of mesenchymal stem cells (MSCs) within cranial sutures.
Zhenkun Weng +6 more
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P38α MAPK-induced senescence in cranial suture progenitor cells promotes craniosynostosis [PDF]
Communications BiologyCraniosynostosis is a congenital cranial developmental disorder that frequently leads to craniofacial deformities and even neurological dysfunction. The abnormalities in cranial suture progenitor cells (SPC) are considered a key event in craniosynostosis;
Zong Chen +9 more
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Difference in anterior fontanelle closure between non-syndromic craniosynostosis and normal controls: a retrospective cross-sectional study [PDF]
Italian Journal of PediatricsBackground This study aimed to investigate the differences in anterior fontanelle closure time and size between children with non-syndromic craniosynostosis and controls on CT imaging. Methods A retrospective cross-sectional study was conducted involving
Jinhua Fu +4 more
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Holographic model of craniosynostosis for HoloLens [PDF]
Acta Cirúrgica BrasileiraPurpose: To develop a holographic skull model of a deformity resulting from craniosynostosis for the HoloLens. Methods: The methodology for product creation and prototyping was the design thinking structured with the double diamond.
Mauricio Mitsuru Yoshida +5 more
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Developments in diagnostic and surgical techniques in children with sagittal suture craniosynostosis: a systematic review spanning the last 30 years [PDF]
Orphanet Journal of Rare DiseasesBackground Sagittal suture craniosynostosis is the most usual subtype of craniosynostosis which results from premature fusion of the sagittal suture. It leads to an elongated skull shape known as scaphocephaly. This condition necessitates timely surgical
Julia Hermann +3 more
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Advances in Clinical Neuroscience & Rehabilitation, 2019 Craniosynostosis is a group of conditions characterised by the premature fusion of one or more cranial vault sutures. This may lead to abnormal cranial development with severe skull and craniofacial deformities and if the condition is left untreated ...
Josephine Jung +4 more
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Detection of a new heterozygous pathogenic NFIA variant in metopic craniosynostosis with preaxial polysyndactyly: A case report [PDF]
JPRAS OpenCraniosynostosis is a congenital condition caused by the early fusion of one or more skull vault sutures during embryological development, resulting in an abnormal head shape. This condition has been linked to many gene variants.
Sipho Simon Nhongo +7 more
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Apert Syndrome: A Case Report [PDF]
Iranian Journal of Neonatology, 2022 Background: Primary craniosynostosis is a form of premature fusion of the cranial sutures, which commonly occurs prenatally. The condition appears in both syndromic and nonsyndromic forms.Case report: The cause of most cases of primary craniosynostosis ...
Shahin Mafinejad +3 more
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European Journal of Human Genetics, 2011 Craniosynostosis, defined as the premature fusion of the cranial sutures, presents many challenges in classification and treatment. At least 20% of cases are caused by specific single gene mutations or chromosome abnormalities. This article maps out approaches to clinical assessment of a child presenting with an unusual head shape, and illustrates how ...
Johnson, D, Wilkie, A
openaire +4 more sources
The clinical manifestations, molecular mechanisms and treatment of craniosynostosis
Disease Models & Mechanisms, 2022 Craniosynostosis is a major congenital craniofacial disorder characterized by the premature fusion of cranial suture(s). Patients with severe craniosynostosis often have impairments in hearing, vision, intracranial pressure and/or neurocognitive ...
Eloise Stanton +3 more
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