Results 51 to 60 of about 15,355 (176)

Mapping the Landscape of Over‐Scanning in CT Imaging: A Scoping Review

Journal of Medical Radiation Sciences, EarlyView.
Over‐scanning in CT is highly prevalent and contributes to unnecessary radiation exposure, with notable impact on radiosensitive organs. Standardised protocols and AI‐assisted planning show strong potential to optimise scan range and reduce excess dose.
Mo'men Bani‐Ahmad, Aoife O Sullivan, Yasser H. Hadi, Laura McLaughlin, Andrew England, Mark McEntee   +5 more
wiley   +1 more source

Transcriptomic Signatures of Single-Suture Craniosynostosis Phenotypes

, 2023
Craniosynostosis is a birth defect where calvarial sutures close prematurely, as part of a genetic syndrome or independently, with unknown cause. This study aimed to identify differences in gene expression in primary calvarial cell lines derived from ...
Jonas A. Gustafson, Alison G. Paquette, Michael L. Cunningham, Samantha Lapehn, Andrew E. Timms, Gustafson, Jonas A., Lapehn, Samantha, Timms, Andrew E., Paquette, Alison G., Cunningham, Michael L.   +9 more
core   +1 more source

Sp1-activated FGFR2 is involved in early-life exposure to nickel-induced craniosynostosis by regulating the ERK1/2 signaling pathway

Environment International
Nickel, a common environmental hazard, is a risk factor for craniosynostosis. However, the underlying biological mechanism remains unclear. Here, we found that early-life nickel exposure induced craniosynostosis in mice.
Zhenkun Weng, Cheng Xu, Xiu Chen, Qing Yan, Zuqiang Fu, Jian Jiao, Jin Xu, Qian Liu, Dongmei Wang, Jingjia Liang, Wenxiang Li, Aihua Gu   +11 more
doaj   +1 more source

Data‐Driven Insights into Hyperkinetic Disorders in Neurodevelopmental Syndromes and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Childhood‐onset hyperkinetic movement disorders occur in a range of genetic conditions. Recently, there has been an increase in recognition of hyperkinetic movement disorders, mainly dystonia, chorea and dyskinesia, with monogenic conditions associated with neurodevelopmental delay (NDD) and also with developmental and epileptic ...
Hugo Morales‐Briceño, Shekeeb S. Mohammad, Rajeshwar Reddy Angiti, Velda Han, Michel Tchan, Russell C. Dale, Victor S.C. Fung   +6 more
wiley   +1 more source

Long-term results in syndromic craniosynostosis [PDF]

, 2012
Skull sutures are fibrous joints between the different bones of the skull. In adult life they have no function but in the foetus they allow the bones to move during the birth process and are involved in skull growth till the age of six years.
Jong, T. (Tim) de
core   +1 more source

Multidisciplinary care of craniosynostosis

Journal of Multidisciplinary Healthcare, 2017
Edward P Buchanan,1 Yunfeng Xue,1 Amy S Xue,1 Asaf Olshinka,1 Sandi Lam2 1Michael E. DeBakey Department of Surgery, Division of Plastic Surgery, 2Michael E. DeBakey Department of Surgery, Division of Neurosurgery, Baylor College of Medicine, Houston, TX,
Buchanan EP, Xue Y, Xue AS, Olshinka A, Lam S   +4 more
doaj  

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source

The management of perioperative pain in craniosynostosis repair: a systematic literature review of the current practices and guidelines for the future

Maxillofacial Plastic and Reconstructive Surgery, 2022
Background Craniosynostosis is a condition characterized by a premature fusion of one or more cranial sutures. The surgical repair of craniosynostosis causes significant pain for the child.
Hatan Mortada, Raghad AlKhashan, Nawaf Alhindi, Haifa B. AlWaily, Ghada A. Alsadhan, Saad Alrobaiea, Khalid Arab   +6 more
doaj   +1 more source

The Audiologic and Otolaryngologic Phenotype in WHIM Syndrome

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective WHIM syndrome (warts, hypogammaglobulinemia, infections, and myelokathexis syndrome) is an ultra‐rare primary immunodeficiency disease caused by autosomal dominant hyperfunctional mutations in the chemokine receptor CXCR4. Otolaryngologists are frequently consulted to evaluate WHIM patients because of recurrent acute ear and sinus ...
Christopher K. Zalewski, H. Jeffrey Kim, Carmen C. Brewer, Sophia Martinez, Caroline Rieger, Elena Cho, David H. McDermott, Philip M. Murphy   +7 more
wiley   +1 more source

Craniosynostosis - Recognition, clinical characteristics, and treatment [PDF]

, 2017
Craniosynostosis is a developmental craniofacial anomaly, resulting in impairment of brain development and abnormally shaped skull. The main cause of craniosynostosis is premature closure of one or more cranial sutures.
Spazzapan, Peter, Kajdic, Nina, Tomaz Velnar, Peter Spazzapan, Velnar, Tomaz, Nina Kajdic   +5 more
core   +1 more source