Results 1 to 10 of about 232,081 (310)
Cre-ating ways to serotonin [PDF]
Frontiers in Neuroscience, 2010 Almost 50 years ago Dahlstrom and Fuxe discovered serotonergic neurons in the brainstem. Much remains to learn, however, about how serotonin (5-hydroxytryptamine or 5HT) modulates circuit activity. Serotonergic neurons release 5HT throughout the CNS. Accordingly, these cells influence breathing rhythms, body temperature, heart rate, pain, eating, sleep,
William eWisden
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Interfaces Numériques, 2022 L’école publique souhaite mettre dans les mains des élèves des ordinateurs, tablettes ou convertibles pour envisager l’éducation numérique. Les compétences d’usages numériques — au sens de maîtrise de l’utilisation — deviennent alors centrales pour ...
Mathieu Payn +2 more
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Stella‐Cre mice are highly efficient Cre deleters [PDF]
genesis, 2011 AbstractCre‐loxP recombination is widely used for genetic manipulation of the mouse genome. Here, we report generation and characterization of a new Cre line, Stella‐Cre, where Cre expression cassette was targeted to the 3′ UTR of the Stella locus. Stella is specifically expressed in preimplantation embryos and in the germline.
Liu, Pentao +10 more
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Circulation Research, 2001 Connecting genes and molecular pathways with in vivo physiological endpoints has never been a simple task. Dissecting the effects of the causal from the phenomenal, the environmental from the inherited, the developmental from the postnatal, the primary from the secondary, and the polygenic from the monogenic has been confounding at best.
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Gp1ba-Cre or Pf4-Cre: pick your poison [PDF]
Blood, 2019 In this issue of Blood , Nagy et al developed a novel Gp1ba-Cre mouse that uses the endogenous Gp1ba locus that encodes the glycoprotein Ibα (GPIbα) subunit of the GPib-IX receptor to drive Cre expression in murine megakaryocytes (MKs) for targeted ablation of floxed genes ...
Kandace, Gollomp, Mortimer, Poncz
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Developing an innovative artificial ecosystem in the wetlands of El Rym, Annaba (Algeria): The “3E garden” model for urban resilience [PDF]
E3S Web of ConferencesThe El Rym wetland (Annaba, Algeria) is a vital ecosystem for biodiversity, currently threatened by increasing anthropogenic pressure and the impacts of climate change.
Youbi Amira +6 more
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Differential CRE Expression in Lhrh-cre and GnRH-cre Alleles and the Impact on Fertility in Otx2-Flox Mice [PDF]
Neuroendocrinology, 2019 There is an increasing trend in studies utilizing cell-specific deletion of genes through conditional gene deletion by CRE recombination. Despite numerous advantages, this strategy also has limitations such as ectopic CRE-expression and germline recombination.
Hanne M. Hoffmann +7 more
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Bacteriological Profile and Antimicrobial Susceptibility Pattern of Pus Isolates from Tertiary Care Hospital [PDF]
JLUMHS, 2022 OBJECTIVE: To detect the most frequent bacterial pathogens causing wound infections and monitor their susceptibility profile at a tertiary care hospital in Karachi, Pakistan. METHODOLOGY: A retrospective cross-sectional study spanning 12 months from
Ambreen Fatima +5 more
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Educação Inclusiva da utopia a uma política educacional
Contexto & Educação, 2013 Este texto propõe uma reflexão sobre a Educação Inclusiva, que se apresenta como um novo paradigma educacional, a partir dos princípios estabelecidos pela Constituição Federal de 1988 e pela Lei de Diretrizes e Bases da Educação Nacional, Lei nº 9394/96.
Lenir Santos Schettert
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The Routledge Handbook of Sustainable Real Estate
Journal of Sustainable Real Estate, 2018 The Routledge Handbook of Sustainable Real Estate, 2018, 424 pages, published by ...
Sara Wilkinson +4 more
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