Results 51 to 60 of about 943,536 (329)

Lysine acetyltransferase 5 in EGFR mutated non-small cell lung cancer [PDF]

, 2018
Histone modifications are crucial in activities such as transcriptional activation, gene silencing, and epigenetic cellular memory. In particular, lysine acetylation via lysine (K) acetyltransferases (KATs) has been implicated in cancer development ...
Pan, Gilbert
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A Simulation Study to Investigate the Usefulness of a Novel Stricture Tool for Training Wire Guided Balloon Dilation

Journal of Digestive Endoscopy, 2022
Background and Aims The training in esophageal stricture dilation is difficult to obtain and have few simulation models. The aim of the study was to evaluate a novel stricture simulation for training a wire-guided, controlled radial expansile (CRE ...
Avinash Bhat Balekuduru, Manoj K. Sahu
doaj   +1 more source

The nature of the low-frequency emission of M51: First observations of a nearby galaxy with LOFAR [PDF]

, 2014
The grand-design spiral galaxy M51 was observed with the LOFAR High Frequency Antennas (HBA) and imaged in total intensity and polarisation. This observation covered the frequencies between 115 MHz and 175 MHz.
Adebahr, B., Anderson, J. M., Beck, R., Bonafede, A., Brunetti, G., Brüggen, M., Chyży, K. T., Conway, J., Dettmar, R-J., Enßlin, T., Fletcher, A., Haverkorn, M., Heald, G., Horellou, C., Horneffer, A., Iacobelli, M., Israel, F. P., Junklewitz, H., Jurusik, W., Kuniyoshi, M., Köhler, J., Mulcahy, D. D., Orrú, E., Paladino, R., Pizzo, R., Reich, W., Röttgering, H. J. A., Scaife, A.   +27 more
core   +5 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Research priorities for stillbirth in Australia: outcomes of a national priority setting partnership

BMC Pregnancy and Childbirth
Background Stillbirth research priorities for Australia were identified in 2015. A renewed priority setting exercise identified current research priorities to address the national burden of stillbirth.
Kirstin Tindal, Fran Boyle, Christine Andrews, Chrissie Astell, Jane Yelland, Sarah McIntyre, Bec Jenkinson, Sean Seeho, Miranda Davies-Tuck, Deanna Stuart-Butler, Philipa Middleton, David Ellwood, Adrienne Gordon, Vicki Flenady   +13 more
doaj   +1 more source

Treatment of Ventriculitis and Meningitis After Neurosurgery Caused by Carbapenem-Resistant Enterobacteriaceae (CRE): A Challenging Topic

Infection and Drug Resistance, 2023
Cuiling Li, Peng Zhou, Yuanqin Liu, Lei Zhang Department of Neurosurgery, Shandong Medicine and Health Key Laboratory of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan ...
Li C, Zhou P, Liu Y, Zhang L
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Investigation of Antibiotics Susceptibility and Resistance Pattern of ESBL and CRE Producing Escherichia coli and Klebsiella pneumonia Isolates from Northern Region of Saudi Arabia

Journal of Pure and Applied Microbiology
The presence of ESBLs and CRE in E. coli and Klebsiella pneumoniae poses a significant challenge in healthcare and community settings. These enzymes can confer resistance to multiple antibiotics, limiting treatment options for infections caused by these ...
Samreen Soomro, Amani Alluhyimt Alanazi, Najd Meshal Alshammari, Athar Mohammad Alanzi, Fai Fahad, Hajer Farhan, Lama Saud Alrashidi, Shatha Obaidullah, Nawaf Al Otaibi   +8 more
doaj   +1 more source

Emergence of a Clinical Escherichia coli Sequence Type 131 Strain Carrying a Chromosomal blaKPC–2 Gene

Frontiers in Microbiology, 2020
Objectives: Bacteria carrying the Klebsiella pneumoniae carbapenemase genes have rapidly spread worldwide and have become a great threat to public health. The blaKPC–2 gene has been primarily located on plasmids cocirculating in various strains. However,
Dairong Wang, Dairong Wang, Xinli Mu, Xinli Mu, Ying Chen, Ying Chen, Dongdong Zhao, Dongdong Zhao, Ying Fu, Ying Fu, Yan Jiang, Yan Jiang, Yiwei Zhu, Yiwei Zhu, Jingjing Quan, Jingjing Quan, Xiaoting Hua, Xiaoting Hua, Guofeng Mao, Xi Li, Yunsong Yu, Yunsong Yu   +21 more
doaj   +1 more source