Patient safety and estimation of renal function in patients prescribed new oral anticoagulants for stroke prevention in atrial fibrillation [PDF]
, 2013 OBJECTIVE: In clinical trials of dabigatran and rivaroxaban for stroke prevention in atrial fibrillation (AF), drug eligibility and dosing were determined using the Cockcroft-Gault equation to estimate creatine clearance as a measure of renal function ...
Ashman, N +6 more
core +2 more sources
Detection of Metabolites by Proton Ex Vivo NMR, in Vivo MR Spectroscopy Peaks and Tissue Content Analysis: Biochemical-Magnetic Resonance Correlation: Preliminary Results [PDF]
, 2009 *Aim*: Metabolite concentrations by in vivo magnetic resonance spectroscopy and ex vivo NMR spectroscopy were compared with excised normal human tissue relaxation times and tissue homogenate contents. *Hypothesis*: Biochemical analysis
Arun Agrawala +2 more
core +1 more source
Effect of Concomitant 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase Inhibitor Therapy on Creatine Phosphokinase Levels and Mortality Among Patients Receiving Daptomycin: Retrospective Cohort Study. [PDF]
, 2014 IntroductionThe prescribing information for daptomycin recommends discontinuing statin therapy during receipt of daptomycin. The literature supporting this recommendation is sparse.
Lodise, Thomas +4 more
core +1 more source
Nutrients, 2019 To accommodate the loss of the plethora of functions of the kidneys, patients with chronic kidney disease require many dietary adjustments, including restrictions on the intake of protein, phosphorus, sodium and potassium.
A. Post, D. Tsikas, S. Bakker
semanticscholar +1 more source
Interference by creatine with determination of serum creatine kinase.
Clinical Chemistry, 1976 We assayed creatine kinase (EC 2.7.3.2) activity in normal serum and in specimens obtained from patients with high serum creatinine by four automated methods: (a) the Technicon SMA 12/60, (b) the Technicon AutoAnalyzer Ii, (c) the Abbott Bichromatic Analyzer, and ( the Aminco Rotochem. Activity blanks were assayed with the AutoAnalyzer II system.
D J Adler, H M Goldschmidt, R W Lent
openaire +3 more sources
Frequency Domain Properties and Fundamental Limits of Buffer-Feedback Regulation in Biochemical Systems [PDF]
arXiv, 2018 Feedback regulation in biochemical systems is fundamental to homeostasis, with failure causing disease or death. Recent work has found that cooperation between feedback and buffering---the use of reservoirs of molecules to maintain molecular concentrations---is often critical for biochemical regulation, and that buffering can act as a derivative or ...
arxiv
Determination of creatinine and creatine by capillary electrophoresis : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University [PDF]
, 1998 The assessment of creatinine and creatine in biological fluids is important in the evaluation of renal and muscular functions. For routine creatinine determinations in the clinical laboratory, the most frequently used method is the spectrophotometric one
Guo, Hong
core
Frontiers in Nutrition, 2019 Sarcopenia is an age-related muscle condition characterized by a reduction in muscle quantity, force generating capacity and physical performance. Sarcopenia occurs in 8–13% of adults ≥ 60 years of age and can lead to disability, frailty, and various ...
D. Candow +5 more
semanticscholar +1 more source
Nitrogen metabolism of the isolated tissues of the rat [PDF]
, 1935 Little study has been devoted to the anabolic aspects of nitrogen metabolism in animals. The reason, of course, has been the difficulty of obtaining experimental conditions in which these can be observed, measured, and analyzed.
Borsook, Henry, Jeffreys, Cecil E. P.
core
Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine [PDF]
, 2017 Aims: Creatine buffers cellular adenosine triphosphate (ATP) via the creatine kinase reaction. Creatine levels are reduced in heart failure, but their contribution to pathophysiology is unclear.
Alfieri +54 more
core +4 more sources