Results 101 to 110 of about 332,672 (384)

Nitrogen metabolism of the isolated tissues of the rat [PDF]

open access: yes, 1935
Little study has been devoted to the anabolic aspects of nitrogen metabolism in animals. The reason, of course, has been the difficulty of obtaining experimental conditions in which these can be observed, measured, and analyzed.
Borsook, Henry, Jeffreys, Cecil E. P.
core  

Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine [PDF]

open access: yes, 2017
Aims: Creatine buffers cellular adenosine triphosphate (ATP) via the creatine kinase reaction. Creatine levels are reduced in heart failure, but their contribution to pathophysiology is unclear.
Alfieri   +54 more
core   +4 more sources

Creatine is a Conditionally Essential Nutrient in Chronic Kidney Disease: A Hypothesis and Narrative Literature Review

open access: yesNutrients, 2019
To accommodate the loss of the plethora of functions of the kidneys, patients with chronic kidney disease require many dietary adjustments, including restrictions on the intake of protein, phosphorus, sodium and potassium.
A. Post, D. Tsikas, S. Bakker
semanticscholar   +1 more source

Development and Breeding of Herbicide‐Resistant Sorghum for Effective Cereal‐Legume Intercropping

open access: yesAdvanced Science, EarlyView.
This study identified two SbALS mutations (A93T and S624N) conferring robust herbicide resistance in sorghum, facilitating efficient weed control. Structural analysis revealed that imazamox resistance is mediated by disrupted herbicide binding. Furthermore, 126 imazamox resistant soybean varieties are screened for sorghum‐soybean intercropping ...
Sanyuan Tang   +20 more
wiley   +1 more source

Methylation of guanidoacetic acid by homocystine plus choline with rat liver slices [PDF]

open access: yes, 1945
The methylation of guanidoacetic acid by liver slices is accelerated by methionine; choline, under these conditions, exerts no significant accelerating effect (1).
Borsook, Henry, Dubnoff, Jacob W.
core  

A metabolomic approach to animal vitreous humor topographical composition: A pilot study [PDF]

open access: yes, 2014
The purpose of this study was to evaluate the feasibility of a 1H-NMR-based metabolomic approach to explore the metabolomic signature of different topographical areas of vitreous humor (VH) in an animal model.
ATZORI, LUIGI   +8 more
core   +1 more source

Variables Influencing the Effectiveness of Creatine Supplementation as a Therapeutic Intervention for Sarcopenia

open access: yesFrontiers in Nutrition, 2019
Sarcopenia is an age-related muscle condition characterized by a reduction in muscle quantity, force generating capacity and physical performance. Sarcopenia occurs in 8–13% of adults ≥ 60 years of age and can lead to disability, frailty, and various ...
D. Candow   +5 more
semanticscholar   +1 more source

The Long Noncoding RNA ΒFaar Promotes White Adipose Tissue Browning and Prevents Diet‐Induced Obesity

open access: yesAdvanced Science, EarlyView.
βFaar selectively targets and inhibits the GTPase activity of the RAB18 protein, thereby reducing LD volume. Conversely, βFaar promotes nuclear translocation of the transcription factor IRF4 in inguinal white adipose tissue (iWAT), facilitating the browning of white adipose tissue and attenuating body fat accumulation.
Yue Yang   +13 more
wiley   +1 more source

Patient safety and estimation of renal function in patients prescribed new oral anticoagulants for stroke prevention in atrial fibrillation [PDF]

open access: yes, 2013
OBJECTIVE: In clinical trials of dabigatran and rivaroxaban for stroke prevention in atrial fibrillation (AF), drug eligibility and dosing were determined using the Cockcroft-Gault equation to estimate creatine clearance as a measure of renal function ...
Ashman, N   +6 more
core   +2 more sources

Creatine and glycerol hyperhydration in trained subjects prior to exercise in the heat. [PDF]

open access: yes, 2007
The authors examined the effects of combined creatine (Cr) and glycerol (Gly) supplementation on responses to exercise in the heat. Subjects (N = 24) were matched for body mass and assigned to either a Cr or placebo (Pl) group. Twice daily during two 7-d
Easton, Chris   +2 more
core  

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