Results 191 to 200 of about 348,599 (377)

Biological sex does not impact intrinsic mitochondrial respiration supported by complexes I and II in human skeletal muscle

Experimental Physiology
The effect of biological sex on rates of skeletal muscle mitochondrial respiration supported by creatine‐dependent phosphate shuttling was previously unknown.
Emily J. Ferguson, Lauren J. Pacitti, Justin Bureau, Callum J. Pufahl, Eveline Menezes, Tanner Stokes, Shivam Gandhi, Luca J. Delfinis, Craig A. Simpson, Christopher G. R. Perry, Brendon J. Gurd, Chris McGlory   +11 more
doaj   +1 more source

Sex-Based Impact of Creatine Supplementation on Depressive Symptoms, Brain Serotonin and SSRI Efficacy in an Animal Model of Treatment-Resistant Depression [PDF]

, 2021
Shami Kanekar, Robert Ettaro, Michael D. Hoffman, Hendrik J. Ombach, Jadeda Brown, Cayla Lynch, Chandni Sheth, Perry F. Renshaw   +7 more
openalex   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka, Jiri Hricko, Lucie Rudl Kulhava, Michaela Paucova, Michaela Novakova, Veronika Hola, Stanislava Rakusanova, Oliver Fiehn, Vojtech Skop, Ivana Lankova, Iva Miskova, Terezie Pelikanova, Martin Haluzik   +12 more
wiley   +1 more source

Causes of creatine kinase levels greater than 1000 IU/L in patients referred to rheumatology

, 2016
David Leverenz, Oana Zaha, Leslie J. Crofford, Cecilia P. Chung   +3 more
openalex   +1 more source

Bioelectrical Impedance Vector and Creatine Phosphokinase Changes Induced by a High-Intensity Training Session in Rink Hockey Players [PDF]

, 2022
Álex Cebrián‐Ponce, Manuel Vicente Garnacho‐Castaño, Mercè Castellano-Fàbrega, Jorge Castizo-Olier, Marta Carrasco‐Marginet, Noemí Serra‐Payá, Alfredo Irurtia   +6 more
openalex   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

A Patient's Post-Cardiovascular Surgery Needs for the Differential Diagnosis of Postoperative Myocardial Ischemia Because of Macro Creatine Kinase

, 2021
Atomu Hino, Azumi Hamasaki, Kozo Morita, Yuki Ichihara, Satoshi Saitou, Hiroshi Niinami   +5 more
openalex   +2 more sources

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis.

Biochemical Journal, 1992
T. Wallimann, M. Wyss, D. Brdiczka, Klaas Nicolay, H. Eppenberger   +4 more
semanticscholar   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source