Results 131 to 140 of about 169,068 (339)
ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li +12 more
wiley +1 more source
Creatine kinase activity in dogs with experimentally induced acute inflammation [PDF]
Journal of BioScience and Biotechnology, 2013 The main purpose of this study was to investigate the effect of acute inflammation on total creatine kinase (CK) activity in dogs. In these animals, CK is an enzyme found predominantly in skeletal muscle and significantly elevated serum activity is ...
Dimitrinka Zapryanova +2 more
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Observations on the Fluorometric Measurement of Creatine Kinase Activity [PDF]
, 1968 Sylvan M Sax, John J. Moore
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The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches
ESC Heart Failure, EarlyView.Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori +9 more
wiley +1 more source
The Thiol Groups and Sub-unit Structure of Creatine Kinase [PDF]
, 1967 Peter M. Bayley, A. R. Thomson
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Epilepsia Open, EarlyView.Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira +5 more
wiley +1 more source
Ketogenic diet for infantile epileptic spasms
Epilepsia Open, EarlyView.Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury +3 more
wiley +1 more source
Serum enzyme studies in muscle disease: Part II Serum creatine kinase activity in muscular dystrophy and in other myopathic and neuropathic disorders [PDF]
, 1964 John Pearce +2 more
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Exploration, EarlyView.The engineered bacteria (2'3'‐cGAMP@E.coli) is designed to synthesize intracellular 2'3'‐cGAMP, enabling the assembly of personalized nanovaccines (nECTs) through a bioconjugation with autologous tumor antigens, circumventing elaborate chemical production processes. The therapeutic impact of nECTs is significantly amplified when combined with a fasting‐
Wenping Huang +7 more
wiley +1 more source
مجله كليه طب الكندي, 2010 Background : It has been suggested that pretreatment with a statin agent prior to myocardial infarction limits myocardial creatine kinase release, and thus may act to limit myocardial infarct size in humans.
Faris Abdul Kareem +2 more
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