Results 201 to 210 of about 612,233 (251)

Outbreak of poisoning by sodium hydrogen methylarsonate (MSMA)—an arsenic‐based herbicide—in horses in Brazil

Equine Veterinary Journal, Volume 58, Issue 5, Page 1258-1268, September 2026.
Abstract Background Arsenic poisoning in horses is rarely reported in the literature. However, arsenic compounds can be present in rodenticides, pesticides, and herbicides, representing a potential source of accidental exposure for horses. Objective To describe the epidemiological, clinical, and laboratory findings from a herd of 31 horses exposed to ...
Gabriella Faria Pereira, Maria Clara Hornich Blimbliem, Anna Laura Previato Rosa Machado, Junara Bianca Rosa Abdala, Geison Morel Nogueira, Hugo Shisei Toma, Tatiane Furtado de Carvalho, Diego José Zanzarini Delfiol   +7 more
wiley   +1 more source

Effectiveness of Resistance Training in People With Down Syndrome: Systematic Review and Meta‐Analysis

Journal of Applied Research in Intellectual Disabilities, Volume 39, Issue 5, September 2026.
ABSTRACT Background We aimed to evaluate the effectiveness of resistance training (RT) in people with Down syndrome (DS) as a way of improving strength, physical and metabolic function, and possible adverse effects. Methods Systematic review and meta‐analysis of RCTs in PubMed, PEDro, Scopus, and WoS databases in September‐2023, registered in PROSPERO (
María Jesús Benzo Iglesias, Lucía Torres Álamo, Alejandro Salazar, Patricia Rocamora Pérez, David Manuel Lucena Antón   +4 more
wiley   +1 more source

Treatment Goals for Primary Biliary Cholangitis, an Australian Perspective

Journal of Gastroenterology and Hepatology, Volume 41, Issue 9, Page 2623-2638, September 2026.
ABSTRACT Primary biliary cholangitis (PBC) is an autoimmune liver disease that targets the small intrahepatic bile ducts with diagnosis based on elevated serum alkaline phosphatase (ALP) levels and the presence of anti‐mitochondrial antibodies. Untreated, it may run a progressive course to cirrhosis and hepatic decompensation, at which point liver ...
Simone I. Strasser, Alexander J. Thompson, Rohit Gupta, John Lubel, Janine French, Beverly Sacks, Martin Weltman   +6 more
wiley   +1 more source

Breaking the Debilitating Cycle: Pathophysiology, Assessment, and Multimodal Intervention of Secondary Debilitation After Hip Fracture in Older Adults—A Narrative Review

Orthopaedic Surgery, Volume 18, Issue 9, Page 1785-1803, September 2026.
This article provides a comprehensive overview of the pathophysiological mechanisms underlying “secondary debilitation after hip fracture,” discusses the clinical application of risk assessment tools, and presents a phased, stepwise intervention strategy aimed at interrupting the “vicious cycle.” ABSTRACT Hip fractures pose a serious threat to the ...
Wenyang Xu, Fan Xu, Maoqiang Fan, Yao Liu, Zhe Song   +4 more
wiley   +1 more source

Integrative simulation analysis of myocardial ischaemia–reperfusion injury

The Journal of Physiology, Volume 604, Issue 18, Page 7640-7662, 15 September 2026.
Abstract figure legend A comprehensive mathematical model of ventricular myocyte was developed to gain insights into the mechanisms underlying cardiac ischaemia–reperfusion injury. The model integrates excitation–contraction (E–C) coupling, cytosolic and mitochondrial pH regulation, pH dependence of major E–C coupling components and cellular energy ...
Takao Shimayoshi, Ayako Takeuchi, Satoshi Matsuoka   +2 more
wiley   +1 more source

Hypoxia‐inducible factor‐1a (HIF1a) as a context‐dependent integrator of metabolic stress in skeletal muscle

The Journal of Physiology, Volume 604, Issue 18, Page 7539-7558, 15 September 2026.
Abstract figure legend Hypoxia‐inducible factor‐1a (HIF1a) integrates physiological and pathological inputs in skeletal muscle, including exercise, circadian timing, cytotoxins and disease. These inputs alter mitochondrial oxidative function, redox state, reactive oxygen species, and local oxygen availability, leading to intermittent or sustained HIF1a
Nicole Welch, Pugazhendhi Kannan, Seshu Vardhan Pothabathula, Annette Bellar, Abhishek A. Chakraborty, Saurabh Mishra, Srinivasan Dasarathy   +6 more
wiley   +1 more source

Early‐stage myocardial changes are not aggravated by Western diet or ageing in Mybpc3 c.2373insG heterozygous mice

The Journal of Physiology, Volume 604, Issue 18, Page 7594-7639, 15 September 2026.
Abstract figure legend Schematic overview of the results. The disease‐modifying effects were investigated by subjecting wild‐type (WT) and heterozygous (HET) Mybpc32373InsG mice to a Western diet for 10 weeks and, in a parallel experiment, ageing them up to 18 months.
Floor W. van den Dolder, Edgar E. Nollet, Vincent A. J. Warnaar, Valentijn J. Jansen, Etto C. Eringa, Bram F. Coolen, Gustav J. Strijkers, Diederik W. D. Kuster, Jolanda van derVelden   +8 more
wiley   +1 more source

Creatine Deficiency Syndromes: Clinical Spectrum, Neuroimaging Features and Treatment Response. [PDF]

Int J Dev Neurosci
Burgac E, Çelik MY, Bulut FD, Kaplan İ, Köseci B, Kara E, Gündüz NT, Mert GG, Kaya Ö, Kor D, Mungan NÖ.   +10 more
europepmc   +1 more source

From extracellular entry to intracellular release: A water-assisted transport cycle for creatine in SLC6A8. [PDF]

Protein Sci
Poudel P, Panday SK, Alexov E.
europepmc   +1 more source

Spectrum of inherited metabolic disorders diagnosed through newborn screening and symptomatic referrals in Eastern Türkiye. [PDF]

Mol Genet Metab Rep
Arslan S, Ekinci Uğan F, Yaralı O, Kahveci H.   +3 more
europepmc   +1 more source