Tubular secretion of creatinine and kidney function: an observational study. [PDF]
, 2020 BackgroundPrior papers have been inconsistent regarding how much creatinine clearance (CrCl) overestimates glomerular filtration rate (GFR). A recent cross-sectional study suggested that measurement error alone could entirely account for the longstanding
Hsu, Chi-Yuan +5 more
core
Clinical review: Biomarkers of acute kidney injury: where are we now? [PDF]
, 2012 The recognition that acute kidney injury (AKI) is a significant independent risk factor for morbidity and mortality has resulted in a substantial number of publications over the past 5 years or more.
Forni, LG, Ostermann, M, Philips, BJ
core +1 more source
Cystatin C versus creatinine in determining risk based on kidney function.
New England Journal of Medicine, 2013 BACKGROUND Adding the measurement of cystatin C to that of serum creatinine to determine the estimated glomerular filtration rate (eGFR) improves accuracy, but the effect on detection, staging, and risk classification of chronic kidney disease across ...
M. Shlipak +11 more
semanticscholar +1 more source
Advances in Nano‐Immunomodulatory Systems for the Treatment of Acute Kidney Injury
Advanced Science, EarlyView.Based on the biodegradability and the immunological reactiveness, IMNs can be broadly classified into four categories. The first category includes types of biologically derived materials that cause immunomodulatory action and biodegradability like nanoparticles of cell membranes, extracellular vesicles, and exosomes.
Chenli Zhang +5 more
wiley +1 more source
Quantitative laboratory results: normal or lognormal distribution?
Journal of Laboratory Medicine, 2020 The identification of a suitable distribution model is a prerequisite for the parametric estimation of reference intervals and other statistical laboratory tasks. Classification of normal vs.
Klawonn Frank +2 more
doaj +1 more source
Sum of previous inpatient serum creatinine measurements predicts acute kidney injury in rehospitalized patients [PDF]
arXiv, 2017 Acute Kidney Injury (AKI), the abrupt decline in kidney function due to temporary or permanent injury, is associated with increased mortality, morbidity, length of stay, and hospital cost. Sometimes, simple interventions such as medication review or hydration can prevent AKI. There is therefore interest in estimating risk of AKI at hospitalization.
arxiv
Risk markers by sex for in-hospital mortality in patients with acute coronary syndrome: a machine learning approach [PDF]
arXiv, 2021 Background: Several studies have highlighted the importance of considering sex differences in the diagnosis and treatment of Acute Coronary Syndrome (ACS). However, the identification of sex-specific risk markers in ACS sub-populations has been scarcely studied.
arxiv
Reference intervals for urinary cotinine levels and the influence of sampling time and other predictors on its excretion among italian schoolchildren [PDF]
, 2018 (1) Background: Environmental Tobacco Smoke (ETS) exposure remains a public health problem worldwide. The aims are to establish urinary (u-) cotinine reference values for healthy Italian children, to evaluate the role of the sampling time and of other ...
Andreoli, Roberta +5 more
core +2 more sources
Drug Metabolism And Disposition, 2016 In humans, creatinine is formed by a multistep process in liver and muscle and eliminated via the kidney by a combination of glomerular filtration and active transport.
X. Chu +4 more
semanticscholar +1 more source
Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer
Advanced Science, EarlyView.This study introduces a tumor‐targeted nanomicelle platform (preS1‐pHLIP) that exploits pre‐existing antiviral immunity to combat heterogeneous cancers. By delivering viral antigens to label tumors as virus‐like targets, the nanomicelles activate antiviral B and T cells, triggering in situ tumor lysis.
Lizhuo Zhang +16 more
wiley +1 more source