Results 141 to 150 of about 867,384 (315)

Minor Postoperative Increases of Creatinine Are Associated with Higher Mortality and Longer Hospital Length of Stay in Surgical Patients

Anesthesiology, 2015
Background:Surgical patients frequently experience postoperative increases in creatinine levels. The authors hypothesized that even small increases in postoperative creatinine levels are associated with adverse outcomes.
F. Kork, F. Balzer, C. Spies, K. Wernecke, A. Ginde, J. Jankowski, H. Eltzschig   +6 more
semanticscholar   +1 more source

Efficient and Specific PDGFRβ‐Targeting Dual‐Mode T1‐T2 MRI Nanoprobe for Early Diagnosis of Non‐Alcoholic Fatty Liver

Advanced Science, EarlyView.
The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li, Tongwei Zhang, Tongxiang Tao, Yaxuan Liu, Haining Xia, Sajid ur Rehman, Zeyong Guo, Jing Zhang, Ruiguo Chen, Zhan Zhang, Junfeng Wang, Kun Ma   +11 more
wiley   +1 more source

Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis

The EuroBiotech Journal, 2019
Activated charcoal was microencapsulated with Lactobacillus acidophilus 314 previously adapted for urea uptake. The creatinine removal capacity of this combination microcapsule was evaluated in-vitro in media simulating the small intestine.
Lim Trisna, Ouyang Wei, Martoni Christopher John, Balit Nasri, Prakash Satya   +4 more
doaj   +1 more source

Effect of sodium bicarbonate infusion in off-pump coronary artery bypass grafting in patients with renal dysfunction

Journal of Anaesthesiology Clinical Pharmacology, 2018
Background and Aims: Acute kidney injury (AKI) following cardiac surgery is a major complication resulting in increased morbidity, mortality and economic burden.
Muralidhar Kanchi, Rudresh Manjunath, Jos Maessen, Lloyd Vincent, Kumar Belani   +4 more
doaj   +1 more source

Ultrasound‐Assisted H2 Transmitter Enables Hydrogen‐Gene Therapy to Prevent Anesthesia/Surgery‐Induced Cognitive Impairment

Advanced Science, EarlyView.
Postoperative cognitive dysfunction (POCD) remains a challenge with no effective treatments. This study introduces a novel hydrogen‐gene therapy strategy, combining focused ultrasound and siRNA delivery via hydrogen emitters, to repair neuroinflammation in a precise and controlled manner.
Ruonan Zhan, Yan Fang, Chuyun Lou, Nan Chen, Xuan Mo, Bo Jiao, Mengke Liu, Yangxi Zhao, Weichen Xu, Huixiong Xu, Haohao Yin, Yi Zhang   +11 more
wiley   +1 more source

Seasonal Variation in Physiology Challenges the Notion of Chimpanzees (Pan troglodytes verus) as a Forest-Adapted Species

Frontiers in Ecology and Evolution, 2018
Savanna-mosaic habitats are thought to represent exceptional circumstances for chimpanzees (Pan troglodytes), and owing to the virtues of their habitat as well as peripheral biogeographic location, they are often regarded as marginal to the chimpanzee ...
Erin G. Wessling, Erin G. Wessling, Tobias Deschner, Roger Mundry, Jill D. Pruetz, Jill D. Pruetz, Roman M. Wittig, Roman M. Wittig, Hjalmar S. Kühl, Hjalmar S. Kühl   +9 more
doaj   +1 more source

Creatinine-based definitions: from baseline creatinine to serum creatinine adjustment in intensive care

Critical Care, 2016
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2016. Other selected articles can be found online at http://www.biomedcentral.com/collections/annualupdate2016.
S. de Rosa, S. Samoni, C. Ronco
semanticscholar   +1 more source

Therapeutic Delivery of circDYM by Perillyl Alcohol Nanoemulsion Alleviates LPS‐Induced Depressive‐Like Behaviors

Advanced Science, EarlyView.
PANEs are specifically designed to enhance the brain delivery efficiency of circDYM compared to commercialized lipid nanoparticles (LNPs). Intranasal administration of PANE‐circDYM effectively alleviated LPS‐induced depressive‐like behaviors by mitigating neuroinflammation and promoting neuroplasticity.
Feng Gao, Zhongkun Zhang, Minzi Ju, Liang Bian, Huijuan Wang, Sibo Zhao, Ningbo Cai, Yu Wang, Yanpeng Jia, Ling Shen, Yuan Zhang, Honghong Yao   +11 more
wiley   +1 more source

Towards automated identification of changes in laboratory measurement of renal function: implications for longitudinal research and observing trends in glomerular filtration rate (GFR) [PDF]

arXiv, 2014
Introduction: Kidney function is reported using estimates of glomerular filtration rate (eGFR). However, eGFR values are recorded without reference to the creatinine (SCr) assays used to derive them, and newer assays were introduced at different time points across laboratories in UK. These changes may cause systematic bias in eGFR reported in routinely
arxiv  

Elevated cystatin-C concentration is associated with progression to prediabetes: the Western New York Study [PDF]

, 2007
OBJECTIVE – We conducted a nested case-control investigation to examine if elevated baseline concentrations of cystatin-C predicted progression from normoglycaemia to prediabetes over 6 years of follow-up from the Western New York Health Study. RESEARCH
Dmochowski, Jacek, Donahue, Richard P., Rafalson, Lisa B., Rejman, Karol, Stranges, Saverio, Trevisan, Maurizio   +5 more
core   +1 more source