Results 101 to 110 of about 120,682 (305)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

FREEDOM OF CREATIVITY AND CREATIVE IMAGINATION. MAN AND HIS TIME

open access: yesВысшее образование в России, 2018
Man as a creative personality desires for freedom as well as cognition and creative work as his essence. It should be noted, however, that what we know about ourselves and how we see ourselves are far from being the same thing.
A. E. Razumov
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Arts, creative & cultural initiatives for citizen engagement on climate action: Insights from Ireland's Creative Climate Action Fund

open access: yesCurrent Research in Environmental Sustainability
A national study in Ireland on the impacts of creative and cultural climate action initiatives highlights their potential to act as catalysts for fostering citizen engagement.
J. Mac Mahon   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Knowledge transformers : a link between learning and creativity

open access: yes, 2002
The purpose of this paper is to investigate whether knowledge transformers which are featured in the learning process, are also present in the creative process. This is achieved by reviewing models and theories of creativity and identifying the existence
Sim, Siang Kok, Duffy, Alex H. B.
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Writing with the small, smart screen: Mobile phones, automated editing and holding on to creative agency

open access: yes, 2016
© 2016 Intellect Ltd Article. English language. Media practitioners find themselves in contradictory times. Smartphones that are able to capture highresolution sound and image are facilitating a consistent, abiding and thoughtful practice so that media ...
Frankham, B, Bettina Frankham
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Developing a creative cluster in a post-industrial city : the Creative Industries Development Service (CIDS) and Manchester

open access: yes, 2013
This article takes the establishment and demise of Manchester’s Creative Industries Development Service (CIDS) as an exemplary case study for the ways in which creative industry policy has intersected with urban economic policy over the last decade.
Gu, Xin, O'Connor, Justin
core  

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