Results 21 to 30 of about 116,703 (258)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Implementation and Evaluation of a Collaborative Lyric-Writing Support System Using a Lyric Association Map

open access: yesMultimodal Technologies and Interaction, 2022
In many popular songs, lyrics are an important element. The act of collaborative lyric writing by multiple people may produce richer ideas than creative acts by individuals.
Meguru Yamashita, Kiwamu Sato, Akio Doi
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

HISTORISITAS FILOSOFIS KONSEP PEMAJAKAN DIVIDEN PADA UNDANG-UNDANG CIPTA KERJA

open access: yesJurnal Akuntansi Multiparadigma, 2021
Abstrak - Historisitas Filosofis Konsep Pemajakan Dividen Pada Undang-Undang Cipta Kerja Tujuan Utama - Penelitian ini bertujuan untuk menelusuri historisitas filosofis konsep pemajakan dividen pada undang-undang cipta kerja.
Made Sudarma, I Nyoman Darmayasa
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Act of Impersonation in the Cinema and the Theatre

open access: yesВісник Київського національного університету культури і мистецтв. Серія: Аудіовізуальне мистецтво і виробництво, 2020
The purpose of this research is to identify and summarize the creative stages, components and sequence of impersonation in the cinema and the theatre.
Mykhailo Barnych, Halyna Rozhko
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Listening as a Creative Act [PDF]

open access: yesMusic Theory Online, 2014
Some important theories of music cognition, such as Lerdahl and Jackendoff’s (1983)A Generative Theory of Tonal Music, posit an archetypal listener with an ideal interpretation of musical structure, and many studies of the perception of structure focus on what different listeners have in common.
Smith, Jordan B L   +2 more
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Prosocial Behaviours and Resilience in School Coexistence: Implications of Creative Self-Efficacy and Stress in Adolescents

open access: yesBehavioral Sciences, 2023
Adolescence brings with it a number of problems such as school violence. To reduce stress and increase the well-being of students, it is necessary to enhance certain skills such as prosocial behaviours, resilience, and creative self-efficacy.
Alba González Moreno   +1 more
doaj   +1 more source

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