Results 51 to 60 of about 318,237 (263)

Updating the dynamic framework of thought: Creativity and psychedelics

open access: yesNeuroImage, 2020
Contemporary investigations regard creativity as a dynamic form of cognition that involves movement between the dissociable stages of creative generation and creative evaluation. Our recently proposed Dynamic Framework of Thought (Christoff et al., 2016)
Manesh Girn   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Developing an on-campus creative economy clinic to elevate the quality of existing community service program

open access: yesASEAN Journal of Community Engagement, 2020
The ongoing community service program has not provided optimal and sustainable outcomes that can improve the creative economy sector as a partner, especially in the era of technological disruption.
Andri Zainal   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Books and Discussion Hybrid Space for Creative City

open access: yesIOP Conference Series: Earth and Environmental Science, 2021
AbstractWhen pandemic covid-19 happen, many reading community basecamp are closed. It is because of the danger for the visitors to come. The small reading house can’t provide enough space for visitors to get physical distancing. So it is important to think about future city planning that solve this problem.
openaire   +1 more source

O Ator e o material criativo: possibilidades para transformação

open access: yesPitágoras 500, 2012
This paper is investigates the relationship between the actor and the creative material. In this discussion I consider the notion of how to work with the creative material; how the actor’s contact with such material can transform him; and I see the ...
Liana Ferraz Diniz
doaj  

The Development of the Creative Industries to Create a Competitive Advantage: Studies in Small Business Sector

open access: yesJournal of Economic Development, Environment and People, 2018
Nowadays, developing creative industries is one of the main priority of Indonesia’s economic development plans. The government have been conducting many efforts to push the development of creative industries in Indonesia such as discussion with policy ...
Totok Sasongko   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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