Results 111 to 120 of about 647,155 (304)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Retracted: Research on the Purification of Environmental Pollution by Biomaterials and Its Treatment Methods in the Development of Rural Cultural and Creative Industries. [PDF]

Bioinorg Chem Appl, 2023
And Applications BC.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Impact of Organisational Climate on Employee Well-Being and Healthy Relationships at Work: A Case of Social Service Centres

Administrative Sciences
Multiple studies highlight the crucial role of management of a positive organisational climate, which in turn contributes to employee well-being and healthy workplace relationships and mitigates the occurrence of negative behaviour, including harassment ...
Andrius Janiukštis, Kristina Kovaitė, Tomas Butvilas, Paulius Šūmakaris   +3 more
doaj   +1 more source

The use of intangible heritage and creative industries as a tourism asset in the UNESCO creative cities network. [PDF]

Heliyon, 2023
Arcos-Pumarola J, Paquin AG, Sitges MH.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

The impact of emergency remote teaching on computer games students’ self-efficacy and readiness for online learning during COVID-19 lockdown

Cogent Education
The COVID-19 pandemic prompted a sudden transition to emergency remote teaching, which demanded greater flexibility and learner autonomy among students.
Lee Cheng, Matthew Holland
doaj   +1 more source

Towards a cultural science of videogames: evolutionary social learning

Cultural Science, 2010
This paper outlines a cultural science approach to videogames. Using the example of the independently developed Minecraft, we examine the dimensions of social learning involved in playing videogames that are characterised by relatively unscripted gaming ...
Banks John, Potts Jason
doaj   +1 more source

'The show must go on!': Hustling through the compounded precarity of Covid-19 in the creative industries. [PDF]

Geoforum, 2022
Langevang T, Steedman R, Alacovska A, Resario R, Kilu RH, Sanda MA.   +5 more
europepmc   +1 more source

CREATIVE INDUSTRIES DEBATE

Cultural Studies, 2010
In what follows I am going to argue that the rise of the creative industries has in general been understood too narrowly. This narrow understanding has had implications for the way that a politics of management and labour in the creative industries has been framed and contained, and it has held back an analysis of class struggle in the creative ...
openaire   +3 more sources