Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Innovation and diversity in the digital cultural and creative industries. [PDF]
J Cult Econ (Dordr), 2021 Snowball J, Tarentaal D, Sapsed J.
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Financing the cultural and creative industries through crowdfunding: the role of national cultural dimensions and policies. [PDF]
J Cult Econ (Dordr), 2023 Cicchiello AF, Gallo S, Monferrà S.
europepmc +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
The Innovation and Development Path of Cultural and Creative Industries in Anhui Province, China: Nvivo12-Based Policy Text Analysis. [PDF]
Comput Intell Neurosci, 2022 Zeng H, Zeng H, Yang L.
europepmc +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
SWOT analysis for development strategy for Silamci natural tourism object facilities in Garut
ARTEKS : Jurnal Teknik ArsitekturNatural tourism contributes significantly to GDP (gross domestic product) and is a major part of the Indonesian economy. In 2022, Indonesia ranked 32nd in the Travel and Tourism Development Index (TTDI), indicating a 3.6 percent rise in the GDP ...
Mentari Sucia, Riska Belasunda
doaj +1 more source
Creative Approach to Development: Leveraging the Sino-African Belt and Road Initiatives to Boost Africa's Cultural and Creative Industries for Africa's Development. [PDF]
East Asia (Piscataway), 2023 Edeh EC, Zhao CC, Osidipe A, Lou SZ.
europepmc +1 more source