Results 51 to 60 of about 643,233 (285)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Artificial intelligence in project management: A bibliometric analysis [PDF]
Problems and Perspectives in ManagementThis study explores the integration of artificial intelligence (AI) into project management through a bibliometric analysis of scholarly publications and patents from 2001 to 2024.
Nurkhat Ibadildin +6 more
doaj +1 more source
Culturally conditioned visual communication in creative expression
Creativity Studies, 2020 The human body and its consciousness interacts with a number of external and internal factors, including, among others, the surrounding environment, experienced emotions, those things seen, things that are possessed and touched, and affection that is ...
Ilona Valantinaitė +2 more
doaj +1 more source
Adapting, surviving, discovering: Creative practitioners in the COVID-19 crisis
Journal of Creativity, 2022 This study investigates how the COVID-19 pandemic affected the work and creative practice of individuals who identify as artists, producers or makers.
Valeria Duarte, David Gauntlett
doaj +1 more source
The London Creative Industries [PDF]
, 2008 This lecture draws from the Creative Industries Observatory research on the London creative industries and in particular provides some initial insights into the networks and relationships which exist including organisational structure, size, and location.
Roodhouse, Simon
core
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
The construction of everyday creative identity
Journal of CreativityExploring everyday creative identity is important because everyday creators are often recognized as problem solvers whose fluency and flexibility influences those in their networks.
Mary Kay Culpepper, David Gauntlett
doaj +1 more source
A Report on the Design Sub-Sector in London [PDF]
, 2008 Housed in the School of Creative Enterprise at the London College of Communication (University of the Arts), the Creative Industries Observatory (CIO) is a leading contributor to academic research and analysis within the creative industries, and a source
Cardoso, Eva +7 more
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source