Results 81 to 90 of about 652,157 (334)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
NSW Creative Industries Economic Profile [PDF]
, 2013 Economic profile of the NSW and Australian Creative Industries ...
Dixon, T
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Creative methodologies for understanding a creative industry [PDF]
, 2011 The chapter presents a conceptual framework for the identification and analysis of value creating and value capture systems within creative industry contexts based on theoretical and empirical studies.
Fuller, Ted +2 more
core +1 more source
“Creative?”… “Entrepreneur?” – Understanding the Creative Industries Entrepreneur
Artivate, 2016 This article explores the lived experience of being an entrepreneur in the creative industries. Entrepreneurial and creative organizations are frequently cited as necessary ingredients for thriving economies. While the individual/society nexus has been well documented by entrepreneurship scholars, the experiences of individuals within the creative ...
openaire +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Why do creative industries cluster? An analysis of the determinants of clustering of creative industries [PDF]
Creative industries tend to concentrate mainly around large- and medium-sized cities, forming creative local production systems. The text analyses the forces behind clustering of creative industries to provide the first empirical explanation of the ...
Francesco Capone +2 more
core
Creating Cultures of Innovation: The Digital Creative Industries [PDF]
, 2016 date-added: 2015-03-24 04:16:59 +0000 date-modified: 2015-03-24 04:16:59 +0000date-added: 2015-03-24 04:16:59 +0000 date-modified: 2015-03-24 04:16:59 +0000date-added: 2015-03-24 04:16:59 +0000 date-modified: 2015-03-24 04:16:59 +0000This work was ...
Briscoe, G, Plumbley, M
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Creativity and the experts: New Labour, think tanks, and the policy process [PDF]
, 2009 This article explores the role of expertise in public debate on creative industries policy in the United Kingdom. The first section gives an overview of the emergence of expertise in government and the rise of think tanks, locating this within a wider ...
Schlesinger, P.
core +1 more source