Results 141 to 150 of about 724,139 (300)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Digital Storytelling: an Influential Reading Comprehension and Creativity Tool for the 21st Century Literacy Skills

open access: yesJELTIM (Journal of English Language Teaching Innovations and Materials), 2019
Digital storytelling has been proposed as an influential language learning tool that can facilitate learners’ reading comprehension and creativity.  There is an interplay between digital storytelling and comprehension.  Likewise, there is a connection between digital storytelling and creativity.   However, this chemistry that exists is far more complex
openaire   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

CREATIVE FUN LEARNING AND MOTIVATION FOR ENHANCING READING SKILLS AMONG ASNAF STUDENTS

open access: yesInternational Journal of Education, Psychology and Counseling
Reading skills form the foundation of knowledge acquisition and lifelong learning. However, underprivileged (asnaf) primary school students often face socio-economic challenges that significantly hinder their literacy development. In this context, the edutainment approach, integrating creativity and motivation has the potential to serve as an effective
Mardzelah Makhsin   +2 more
openaire   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

#BookTok’s Peer Pedagogies: Invitations to Learn About Books and Reading on TikTok

open access: yesSocial Media + Society
This article extends the idea of media pedagogies to consider how TikTok provides a site of social learning about books and reading. It uses the concept of “peer pedagogies” to identify how the #BookTok hashtag is used to invite book and reading ...
Michael Dezuanni, Amy Schoonens
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Development of Creativity Skill in Critical Reading with Humanistic Literacy Approach

open access: yes, 2022
Harun Joko Prayitno   +6 more
openaire   +1 more source

The Impact of Reading Activity Before Lesson on Creative Thinking Skill

open access: yesProceedings of the 3rd International Conference on Learning Innovation and Quality Education (ICLIQE 2019), 2020
null Triyanto   +2 more
openaire   +1 more source

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