Results 71 to 80 of about 724,139 (300)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

How to Read and Review a Book like a Qualitative Researcher [PDF]

, 2010
Reading a book with the intention of composing a review demands certain skills on the part of the reader that may differ when the goal of the read is for pleasure or scholarship.
Chenail, Ronald J.
core   +1 more source

BUILDING STUDENTS' SKILLS IN READING POETRY TEXTS WITH CREATIVITY AND INTEREST

Primary Education Journals (Jurnal Ke-SD-An)
The aim of this research is to arouse students' interest in reading poetry through a poetry musicalization approach. The service team conducted a situation analysis with partners and found that students' interest in reading poetry was low due to a lack of understanding and appreciation of poetry and a lack of student creativity in representing poetry ...
Nening Rosline Telaumbanua, Mastawati Ndruru, Darni Marsellin Laowo, Festina Buulolo   +3 more
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

PENGGUNAAN PENDEKATAN LEARNING BY DOING UNTUK MENINGKATKAN KEMAMPUAN MEMBACA PERMULAAN ANAK TUNAGRAHITA RINGAN [PDF]

, 2014
Pembelajaran Bahasa Indonesia di Sekolah Dasar Luar Biasa (SDLB) berdasarkan Kurikulum Tingkat Satuan Pendidikan (KTSP) lebih menekankan keterlibatan anak dalam belajar, hal ini terlihat dalam standar kompentensi yang harus dikuasai oleh siswa yaitu ...
Heryadi, Yadi
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Improving Students’ Reading Skills through the Use of the WFR Activities

HOW, 2008
This Article entitled Improving Students’ Reading Skills through the Use of the WFR Activities is just a very short description of an action research carried out in a public school in Bucaramanga.
Tatiana Mikhailova
doaj  

A STUDY ON THE INDUCTIVE THINKING AS TEACHING MODEL USED \ud BY THE ENGLISH TEACHER IN READING SUBJECT AT SLTPN BANDAR \ud 1 PACITAN [PDF]

, 2007
The information era cannot be separated from the language. The language is the soul of information. The function of language in the society is as a means of communication, which is used by human beings to communicate each other, and most of the ...
Rakhmanto, Sugeng
core