Results 51 to 60 of about 200,908 (303)

Editorial Message

open access: yesGiLE Journal of Skills Development, 2021
No ...
Judit Beke
doaj  

The foundations of environment in Quran with a review of seven United Nations Conferences on the environment

open access: yesEnvironment Conservation Journal, 2015
Although scientists have felt the dangers of environmental degradation from a long time ago and were sure about its’ adverse consequences and the need to change human behavior towards the only livable plant, But in the past four decades have taken ...
Mahmoud Rostami Tabar   +1 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

WEb3 Creator Summit - Guest Speaker

open access: yes, 2023
Panelist on 'What can Web3 for the music industry' and ' Artist funding in ...
Reddington, J.
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Curious users of casual creators [PDF]

open access: yesProceedings of the 13th International Conference on the Foundations of Digital Games, 2018
Casual creators are a type of design tool identified by Compton & Mateas, characterised by an orientation towards enjoyable, intrinsically motivated creative exploration, rather than task-oriented designer productivity. In our experiments holding rapid game jams with Wevva, a casual creator for mobile game design, we have noticed, however, that users ...
Mark J. Nelson   +3 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

THEORY OF CREATION AND THE GENETIC INTEGRITY OF THE WORLD – THE FUTURE OF HUMANITY BASIS OF IDEOLOGY

open access: yesМодернизация, инновация, развитие, 2015
Article describes one of the most difficult problems – the Theory of genetic energy-information unity of the World, according to which the World is the single entity hierarchically organized and directed by the World Creator, appearance of the Creator ...
В. A. Astafyev
doaj   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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