Results 61 to 70 of about 225,562 (293)
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Creator Context for Tweet Recommendation [PDF]
When discussing a tweet, people usually not only refer to the content it delivers, but also to the person behind the tweet. In other words, grounding the interpretation of the tweet in the context of its creator plays an important role in deciphering the
Najork, Marc +8 more
core +1 more source
New forms of technological innovation often come with new concerns about impacts on artistry and creativity, including disruptions to markets, effects on rights relating to creative works, and artists’ changing relationships to their identities and ...
Chris Hubbles +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Interdisciplinaridade e Educação: Ensaio teórico a partir de vários olhares
O presente artigo tem como objetivo realizar uma reflexão sobre a interdisciplinaridade, aplicando-a ao campo da educação. Do ponto de vista metodológico, trata-se de uma reflexão teórica, construída com o apoio de vários pensadores(as), selecionados(as)
José do Nascimento Soares +1 more
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Augmented reality in the slaughterhouse - a future operation facility?
The present case study sums up the results of an initial attempt to adapt the emerging technology of Augmented Reality (AR) for supporting routine operations performed in Danish slaughterhouse facilities. Our aim is to reveal the applicability of off-the-
Lars Bager Christensen +1 more
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source

