Results 61 to 70 of about 225,562 (293)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Creator Context for Tweet Recommendation [PDF]

open access: yes, 2023
When discussing a tweet, people usually not only refer to the content it delivers, but also to the person behind the tweet. In other words, grounding the interpretation of the tweet in the context of its creator plays an important role in deciphering the
Najork, Marc   +8 more
core   +1 more source

Art Official Intelligence: Music and Intellectual Property Philosophy in the New Age of Artificial Intelligence–Assisted Creativity

open access: yesTransactions of the International Society for Music Information Retrieval
New forms of technological innovation often come with new concerns about impacts on artistry and creativity, including disruptions to markets, effects on rights relating to creative works, and artists’ changing relationships to their identities and ...
Chris Hubbles   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Interdisciplinaridade e Educação: Ensaio teórico a partir de vários olhares

open access: yesCadernos Cajuína
O presente artigo tem como objetivo realizar uma reflexão sobre a interdisciplinaridade, aplicando-a ao campo da educação. Do ponto de vista metodológico, trata-se de uma reflexão teórica, construída com o apoio de vários pensadores(as), selecionados(as)
José do Nascimento Soares   +1 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Augmented reality in the slaughterhouse - a future operation facility?

open access: yesCogent Food & Agriculture, 2016
The present case study sums up the results of an initial attempt to adapt the emerging technology of Augmented Reality (AR) for supporting routine operations performed in Danish slaughterhouse facilities. Our aim is to reveal the applicability of off-the-
Lars Bager Christensen   +1 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

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