Results 251 to 260 of about 120,334 (323)

Fasting and Caloric Restriction Activate an ADIOL‐NHR‐91‐Kynurenine Pathway Signaling Axis to Promote Healthspan

Aging Cell, Volume 25, Issue 5, May 2026.
The steroid hormone ADIOL emerges as a key mediator of fasting–and caloric restriction–induced healthspan benefits in C. elegans. These regimens activate ADIOL production, which acts through the estrogen receptor β homolog NHR‐91 to reduce neural kynurenic acid levels and enhance healthspan independently of lifespan. ADIOL supplementation, even late in
Ana Guijarro‐Hernández, Shinja Yoo, George A. Lemieux, Sena Komatsu, Abdullah Q. Latiff, Rishika R. Patil, Kaveh Ashrafi   +6 more
wiley   +1 more source

CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1.

, 1999
Katrine Frønsdal, Nikolai Engedal, Thomas Slagsvold, Fahri Saatcioglu   +3 more
openalex   +1 more source

Role of cyclic AMP response element binding protein (CREB) in angiotensin II-induced responses in vascular smooth muscle cells

, 2020
Vanessa Truong, Madhu B. Anand‐Srivastava, Ashok K. Srivastava   +2 more
openalex   +2 more sources

Calcineurin controls the expression of numerous genes in cerebellar granule cells [PDF]

, 2003
Ashby, Dominique S, Freeman, Tom C, Fresu, Luigia, Genazzani, Armando A, Kramer, Dana   +4 more
core   +1 more source

Sex‐Dependent Effects of Angiotensin II and Calcineurin in the Vasculature of Mice

Acta Physiologica, Volume 242, Issue 5, May 2026.
ABSTRACT Aim Cardiovascular diseases display strong sex differences. Angiotensin II (AngII) is implicated in this process. The ubiquitously expressed enzymatic beta subunit of calcineurin (PPP3CB), a serine/threonine phosphatase, can mediate pathological effects of AngII in the heart.
Alexander Nolze, Sindy Rabe, Stefanie Ruhs, Nicole Strätz, Katja Quarch, Conny Köhler, Claudia Grossmann   +6 more
wiley   +1 more source

A Splice Variant of Stress Response Gene ATF3 Counteracts NF-κB-dependent Anti-apoptosis through Inhibiting Recruitment of CREB-binding Protein/p300 Coactivator

, 2005
Bayin Hua, Mimi Tamamori‐Adachi, Yang Luo, Kiyoshi Tamura, M. Morioka, Mizue Fukuda, Yujiro Tanaka, Shigetaka Kitajima   +7 more
openalex   +1 more source

Increased expression of the androgen receptor with p300 and interleukin-6 coactivators compensate for oligonucleotide suppression of bcl-2: no increased CREB binding protein or interleukin-4 expression [PDF]

, 2012
Marvin Rubenstein, Courtney M.P. Hollowell, Patrick Guinan   +2 more
openalex   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, Volume 183, Issue 10, Page 2177-2196, May 2026.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Role of Hypothalamic Creb-Binding Protein in Obesity and Molecular Reprogramming of Metabolic Substrates. [PDF]

PLoS One, 2016
Moreno CL, Yang L, Dacks PA, Isoda F, Deursen JM, Mobbs CV.   +5 more
europepmc   +1 more source

Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein [PDF]

, 2016
Alexander S. Krois, Josephine C. Ferreon, Maria A. Martinez‐Yamout, H. Jane Dyson, Peter E. Wright   +4 more
openalex   +1 more source