Results 261 to 270 of about 120,334 (323)

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, Volume 183, Issue 9, Page 1727-1746, May 2026.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

CREB-binding protein plays key roles in juvenile hormone action in the red flour beetle, Tribolium Castaneum. [PDF]

Sci Rep, 2018
Xu J, Roy A, Palli SR.
europepmc   +1 more source

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, Volume 183, Issue 9, Page 1747-1778, May 2026.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

Two Distinct Nuclear Receptor-Interaction Domains and CREB-Binding Protein-Dependent Transactivation Function of Activating Signal Cointegrator-2 [PDF]

, 2001
Soo‐Kyung Lee, Sung Yun Jung, Youn-Sung Kim, Soon-Young Na, Young Chul Lee, Jae Woon Lee   +5 more
openalex   +1 more source

OSA Initiates Histone Lactylation That Drives PDE4B/FUS/AGT Axis to Pulmonary Hypertension

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study illustrates how chronic intermittent hypoxia (CIH) in obstructive sleep apnea (OSA) leads to hypertension via increased oxidative stress and mitochondrial dysfunction in pulmonary artery smooth muscle cells (PASMCs), causing glycolytic dysregulation. Lactate accumulation enhances histone lactylation, upregulating phosphodiesterase 4B (PDE4B),
Li Yang, Qing Ni, Yan He, Shijie Liu, Lulu Gan, Anni Dai, Yang Hu, Qian Liu, Xueling Yang, Jiqian Li, Yi Tao, Yunyu Li, Mingyue Xu   +12 more
wiley   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

Fetuin‐b Mediates Lipid Overload‐Induced Hepatic Lipid Accumulation in Large Yellow Croaker (Larimichthys crocea)

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Schematic of the mechanism of fetuin‐b mediated high‐fat diet‐induced hepatic steatosis in Larimichthys crocea. Lipid overload triggers C/EBPα‐mediated fetuin‐b upregulation. Fetuin‐b drives hepatic lipid accumulation by reprogramming lipid metabolism and inhibiting Plin2 ubiquitination to stabilize lipid droplets, identifying it as a potential ...
Yanan Shen, Qiuchi Chen, Zengqi Zhao, Qiang Chen, Yuhang Tang, Fan Chen, Tingting Hao, Jianlong Du, Qinghui Ai   +8 more
wiley   +1 more source

Exploitation of CREB signaling by HTLV-1 and BLV: A central axis in viral persistence and leukemogenesis. [PDF]

Med Oncol
Farjami Z, Akbarin MM.
europepmc   +1 more source

CREB-binding protein (CBP) phosphorylation by Protein Kinase M zeta (PKMzeta) in nucleus as a mechanism of memory maintenance

, 2019
Dae Hee Han, Jun-Yeong Beak, Bong‐Kiun Kaang   +2 more
openalex   +1 more source

Improved Activities of CREB Binding Protein, Heterogeneous Nuclear Ribonucleoproteins and Proteasome Following Downregulation of Noncoding hsrω Transcripts Help Suppress Poly(Q) Pathogenesis in Fly Models. [PDF]

Genetics, 2019
europepmc   +1 more source