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Evidence of dysregulation of the CREB/CRE transcriptional pathway in animal models of Huntington's disease (HD) suggests that strategies designed to augment CRE-mediated transcription may be of therapeutic value. Here, we investigated the consequences of
Yun-Sik Choi +2 more
exaly +3 more sources
Dopamine is a brain neurotransmitter involved in the pathology of schizophrenia. The dopamine hypothesis states that, in schizophrenia, dopaminergic signal transduction is hyperactive.
Haitao Wang +2 more
exaly +3 more sources
Effect of vitamin D supplementation on CREB-TrkB-BDNF pathway in the hippocampus of diabetic rats [PDF]
Objective(s): Cyclic AMP (adenosine monophosphate) response element-binding protein (CREB) and Brain-derived neurotrophic factor (BDNF) are reported to broadly involve in learning capacity and memory.
Hoda Nadimi +8 more
doaj +1 more source
Microsphere incorporation as a strategy to tune the biological performance of bioinks
Although alginate is widely used as a matrix in the formulation of cell-laden inks, this polymer often requires laborious processing strategies due to its lack of cell adhesion moieties.
Mar Bonany +3 more
doaj +1 more source
MiR-2b-2-5p regulates lipid metabolism and reproduction by targeting CREB in Bactrocera dorsalis
In female animals, metabolic homoeostasis and reproductive fitness are critical to population expansion. The trade-off between lipid storage and reproduction inevitably occurs.
Shengfeng Zhang +4 more
doaj +1 more source
The effect of high-intensity interval swimming training on CREB and ERK proteins of hippocampus tissue in elderly rats [PDF]
Background and Purpose: Cognitive impairment caused by aging has become one of the most common health threats in many countries. Signaling pathways are important moderators of various physiological and pathological processes, and abnormal activation of ...
Zahra Sabri, Mozhgan Ahmadi
doaj +1 more source
The impact of moderate-intensity swimming exercise on learning and memory in aged rats: The role of Sirtuin-1 [PDF]
Objective(s): The purpose of this study was to evaluate the effect of moderate-intensity swimming exercise on learning and memory by the Morris water maze test.
Ulker Tunca +4 more
doaj +1 more source
Choosing Strategies to Deal with Artifactual EEG Data in Children with Cognitive Impairment
Rett syndrome is a disease that involves acute cognitive impairment and, consequently, a complex and varied symptomatology. This study evaluates the EEG signals of twenty-nine patients and classify them according to the level of movement artifact.
Ana Tost +6 more
doaj +1 more source
Fatiga oligocíclica de la aleación Ti6Al4V nitrurada termoquímicamente
El uso del titanio y sus aleaciones en aplicaciones con existencia de fricción es limitado, debido a su baja dureza y malas propiedades tribológicas. Existen diversos tratamientos superficiales capaces de corregir dichos problemas, como el tratamiento ...
D. Rodríguez +3 more
doaj +1 more source
Les assignatures vinculades a l’estudi de la macroeconomia solen resultar especialment àrides per als alumnes a causa de l’elevat aparell analític necessari per al desenvolupament del programa. Per això, en aquest article proposem una pràctica en la que:
Xavier Raurich, Hector Sala
doaj +1 more source

