Results 1 to 10 of about 77,411 (161)
CREB − a real culprit in oncogenesis [PDF]
FEBS Journal, 2007 The cAMP response element‐binding protein (CREB) is a stimulus‐induced transcription factor that responds rapidly to phosphorylation and/or coactivator activation. Regulated activation of CREB has a significant impact on cellular growth, proliferation and survival.
Jin Dy
exaly +5 more sources
Neurobiology of Disease, 2009 Evidence of dysregulation of the CREB/CRE transcriptional pathway in animal models of Huntington's disease (HD) suggests that strategies designed to augment CRE-mediated transcription may be of therapeutic value. Here, we investigated the consequences of
Kari Hoyt, Bo Young Lee, Karl Obrietan
exaly +3 more sources
Effect of vitamin D supplementation on CREB-TrkB-BDNF pathway in the hippocampus of diabetic rats [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Cyclic AMP (adenosine monophosphate) response element-binding protein (CREB) and Brain-derived neurotrophic factor (BDNF) are reported to broadly involve in learning capacity and memory.
Hoda Nadimi +8 more
doaj +1 more source
Microsphere incorporation as a strategy to tune the biological performance of bioinks
Journal of Tissue Engineering, 2022 Although alginate is widely used as a matrix in the formulation of cell-laden inks, this polymer often requires laborious processing strategies due to its lack of cell adhesion moieties.
Mar Bonany +3 more
doaj +1 more source
Critical Reviews™ in Oncogenesis, 2011 Acute myeloid leukemia (AML) is one of the most common leukemias with a 20% 5-year event-free survival in adults and 50% overall survival in children, despite aggressive chemotherapy treatment and bone marrow transplantation. The incidence and mortality rates for acute leukemia have only slightly decreased over the last 20 years, and therefore greater ...
Er-Chieh, Cho +2 more
openaire +2 more sources
MiR-2b-2-5p regulates lipid metabolism and reproduction by targeting CREB in Bactrocera dorsalis
RNA Biology, 2023 In female animals, metabolic homoeostasis and reproductive fitness are critical to population expansion. The trade-off between lipid storage and reproduction inevitably occurs.
Shengfeng Zhang +4 more
doaj +1 more source
The effect of high-intensity interval swimming training on CREB and ERK proteins of hippocampus tissue in elderly rats [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2023 Background and Purpose: Cognitive impairment caused by aging has become one of the most common health threats in many countries. Signaling pathways are important moderators of various physiological and pathological processes, and abnormal activation of ...
Zahra Sabri, Mozhgan Ahmadi
doaj +1 more source
The impact of moderate-intensity swimming exercise on learning and memory in aged rats: The role of Sirtuin-1 [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): The purpose of this study was to evaluate the effect of moderate-intensity swimming exercise on learning and memory by the Morris water maze test.
Ulker Tunca +4 more
doaj +1 more source
Choosing Strategies to Deal with Artifactual EEG Data in Children with Cognitive Impairment
Entropy, 2021 Rett syndrome is a disease that involves acute cognitive impairment and, consequently, a complex and varied symptomatology. This study evaluates the EEG signals of twenty-nine patients and classify them according to the level of movement artifact.
Ana Tost +6 more
doaj +1 more source
Fatiga oligocíclica de la aleación Ti6Al4V nitrurada termoquímicamente
Revista de Metalurgia, 2001 El uso del titanio y sus aleaciones en aplicaciones con existencia de fricción es limitado, debido a su baja dureza y malas propiedades tribológicas. Existen diversos tratamientos superficiales capaces de corregir dichos problemas, como el tratamiento ...
D. Rodríguez +3 more
doaj +1 more source