Studying the Effect of Lactobacillus fermentum on Arc and CREB Genes Expression of Involved in The Memory of Alzheimer\'s Rats [PDF]
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2023 Introduction: Alzheimer's disease is a common progressive neurogenerative disease that leads to dementia and destruction of brain cells, especially in areas related to learning and memory such as the hippocampus.
Elnaz Mogaddam +3 more
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p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner. [PDF]
, 2017 Bone mass is determined by the balance between bone formation, carried out by mesenchymal stem cell-derived osteoblasts, and bone resorption, carried out by monocyte-derived osteoclasts.
Ao, Junping +9 more
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Dexamethasone-Induced Expression of Endothelial Mitogen-Activated Protein Kinase Phosphatase-1 Involves Activation of the Transcription Factors Activator Protein-1 and 3',5'-Cyclic Adenosine 5'-Monophosphate Response Element-Binding Protein and the Generation of Reactive Oxygen Species [PDF]
, 2008 We have recently identified the MAPK phosphatase (MKP)-1 as a novel mediator of the antiinflammatory properties of glucocorticoids (dexamethasone) in the human endothelium. However, nothing is as yet known about the signaling pathways responsible for the
Abraham +36 more
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Ending Restenosis: Inhibition of Vascular Smooth Muscle Cell Proliferation by cAMP
Cells, 2019 Increased vascular smooth muscle cell (VSMC) proliferation contributes towards restenosis after angioplasty, vein graft intimal thickening and atherogenesis.
Sarah A. Smith +2 more
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Extinction of gene expression in somatic cell hybrids. a reflection of important regulatory mechanisms? [PDF]
, 1993 Extinction in somatic cell hybrids is a multifactorial process that leads to loss of cell-type-specific gene expression. The underlying mechanisms are thought to mirror, at least in part, the repertoire of regulatory mechanisms controlling mammalian cell
Boshart, Michael +2 more
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Nature and Science of Sleep, 2021 Hui Shen, Yanling Meng, Dan Liu, Zheng Qin, Hong Huang, Lei Pan, Wei Wang, Jian Kang Institute of Respiratory Disease, The First Hospital of China Medical University, Shenyang, People’s Republic of ChinaCorrespondence: Wei WangInstitute of ...
Shen H +7 more
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DHA (omega-3 fatty acid) increases the action of brain-derived neurotrophic factor (BDNF)
Oilseeds and fats, crops and lipidsNeurons have high energy needs, requiring a continuous supply of glucose from the blood. Tight regulation of glucose metabolism in response to stimuli is essential for brain physiology.
Majou Didier, Dermenghem Anne-Lise
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PABPN1 functions as a downstream gene of CREB to inhibit the proliferation of preadipocytes [PDF]
Animal BioscienceObjective This study was conducted to reveal the role of nuclear poly(A) binding protein 1 (PABPN1) in the proliferation of preadipocytes, and to reveal the relationship between PABPN1 and cAMP response element (CRE)-binding protein (CREB) in the ...
Xiao-Han Zhang +7 more
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Multiple mRNA isoforms of the transcription activator protein CREB [PDF]
, 1992 We have characterized cDNA clones representing mouse CREB (cyclic AMP responsive element binding protein) mRNA isoforms. These include CREBA and CREBa, of which the rat and human homologues have been previously identified.
Boshart, Michael +4 more
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Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons. [PDF]
, 2015 Previous studies have revealed a critical role for CREB-regulated transcriptional coactivator (CRTC1) in regulating neuronal gene expression during learning and memory. CRTC1 localizes to synapses but undergoes activity-dependent nuclear translocation to
Ch'ng, Toh Hean +5 more
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