Results 11 to 20 of about 87,086 (298)
Annual Review of Neuroscience, 1998 ▪ Abstract The cAMP responsive element binding protein (CREB) is a nuclear protein that modulates the transcription of genes with cAMP responsive elements in their promoters. Increases in the concentration of either calcium or cAMP can trigger the phosphorylation and activation of CREB.
A J, Silva +3 more
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CREB, neurogenesis and depression
BioEssays, 2007 AbstractThe transcription factor CREB has been implicated in signalling pathways relevant for pathogenesis and therapy of depression. CREB is upregulated and activated in the hippocampus by chronic antidepressant treatment, similarly as neurogenesis.
P. Gass, M.A. Riva
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Early induction of CREB activation and CREB-regulating signalling by antidepressants
The International Journal of Neuropsychopharmacology, 2009 Converging evidence points to adaptive changes in neuroplasticity and gene expression as mediators of therapeutic action of antidepressants. Activation of cAMP response-element binding protein (CREB) and CREB-regulating signalling are considered main effectors in these mechanisms.
D. Tardito +5 more
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CREB Regulates Distinct Adaptive Transcriptional Programs in Astrocytes and Neurons [PDF]
Scientific Reports, 2017 The cyclic AMP response element binding protein (CREB) is a primary hub of activity-driven genetic programs in neurons controlling plasticity, neurogenesis and survival. By contrast, the gene networks coordinated by CREB in astrocytes are unknown despite
Luis Pardo +7 more
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Change of MicroRNA-134, CREB and p-CREB expression in epileptic rat
Asian Pacific Journal of Tropical Medicine, 2015 To To investigate the changes of MicroRNA-134, CREB and p-CREB expression in epileptic rat brains in order to elucidate the molecular mechanisms of epilepsy, providing new ideas for clinical treatment.Sixty-four Spraque-Dawley (SD) rats were divided into groups randomly, including control group, six hours after seizure group, 24-hour group, three-day ...
Zhu, Yan +3 more
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Critical Reviews™ in Oncogenesis, 2011 Acute myeloid leukemia (AML) is one of the most common leukemias with a 20% 5-year event-free survival in adults and 50% overall survival in children, despite aggressive chemotherapy treatment and bone marrow transplantation. The incidence and mortality rates for acute leukemia have only slightly decreased over the last 20 years, and therefore greater ...
Er-Chieh, Cho +2 more
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Molecular and functional characterization of an evolutionarily conserved CREB-binding protein in the Lymnaea CNS [PDF]
, 2022 In eukaryotes, CREB-binding protein (CBP), a coactivator of CREB, functions both as a platform for recruiting other components of the transcriptional machinery and as a histone acetyltransferase (HAT) that alters chromatin structure. We previously showed
Kemenes, I. +14 more
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Propagación de grietas por fatiga de cementos óseos acrílicos. Influencia de los agentes radiopacos
Revista de Metalurgia, 2001 En este trabajo se propone el monómero 2,5-diyodo-8-quinolina metacrilato (IHQM) como nuevo agente radiopaco. La adición del agente yodado proporciona un aumento en la resistencia a la tracción, en la tenacidad a la fractura y en la ductilidad con ...
M. P. Ginebra +6 more
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A Novel Spatial Feature for the Identification of Motor Tasks Using High-Density Electromyography
Sensors, 2017 Estimation of neuromuscular intention using electromyography (EMG) and pattern recognition is still an open problem. One of the reasons is that the pattern-recognition approach is greatly influenced by temporal changes in electromyograms caused by the ...
Mislav Jordanić +4 more
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Calcium carbonate supplementation causes memory impairment in mice
Asian Pacific Journal of Tropical Medicine, 2018 Objective: To investigate the influence of calcium carbonate supplementation on cognitive function in mice. Methods: Mice were fed diets containing 1.0% calcium carbonate for 8 weeks, following which they were evaluated for memory function using object ...
Yasushi Hasegawa +2 more
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