Early induction of CREB activation and CREB-regulating signalling by antidepressants
The International Journal of Neuropsychopharmacology, 2009 Converging evidence points to adaptive changes in neuroplasticity and gene expression as mediators of therapeutic action of antidepressants. Activation of cAMP response-element binding protein (CREB) and CREB-regulating signalling are considered main effectors in these mechanisms.
D. Tardito +5 more
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CREB Regulates Distinct Adaptive Transcriptional Programs in Astrocytes and Neurons [PDF]
Scientific Reports, 2017 The cyclic AMP response element binding protein (CREB) is a primary hub of activity-driven genetic programs in neurons controlling plasticity, neurogenesis and survival. By contrast, the gene networks coordinated by CREB in astrocytes are unknown despite
Luis Pardo +7 more
doaj +2 more sources
Change of MicroRNA-134, CREB and p-CREB expression in epileptic rat [PDF]
Asian Pacific Journal of Tropical Medicine, 2015 To To investigate the changes of MicroRNA-134, CREB and p-CREB expression in epileptic rat brains in order to elucidate the molecular mechanisms of epilepsy, providing new ideas for clinical treatment.Sixty-four Spraque-Dawley (SD) rats were divided into groups randomly, including control group, six hours after seizure group, 24-hour group, three-day ...
Zhu, Yan +3 more
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Anàlisi de l'expressió de NOR-1 en les cèl·lules musculars llises i de la seva implicació en la proliferació cel·lular [PDF]
, 2004 [cat] Dado que las células musculares lisas vasculares (CMLV) juegan un papel clave en el desarrollo de la aterosclerosis, conocer los genes que regulan la proliferación y migración de estas células pude conducir a encontrar nuevas dianas farmacológicas ...
Rius Capalvo, Jordi
core +7 more sources
Paternal Sperm Gnas-ICR Epigenetic Programming Contributes to PPP-Like Phenotypes in Female Offspring. [PDF]
Adv Sci (Weinh)A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Huang J, Chen L, Wu T, Li Y, Wang H.
europepmc +2 more sources
@tic: Revista d'Innovació Educativa, 2010 Les assignatures vinculades a l’estudi de la macroeconomia solen resultar especialment àrides per als alumnes a causa de l’elevat aparell analític necessari per al desenvolupament del programa. Per això, en aquest article proposem una pràctica en la que:
Xavier Raurich, Hector Sala
doaj +1 more source
Learning and nicotine interact to increase CREB phosphorylation at the jnk1 promoter in the hippocampus [PDF]
, 2012 Nicotine is known to enhance long-term hippocampus dependent learning and memory in both rodents and humans via its activity at nicotinic acetylcholinergic receptors (nAChRs).
Rachel L Poole +14 more
core +1 more source
Propagación de grietas por fatiga de cementos óseos acrílicos. Influencia de los agentes radiopacos
Revista de Metalurgia, 2001 En este trabajo se propone el monómero 2,5-diyodo-8-quinolina metacrilato (IHQM) como nuevo agente radiopaco. La adición del agente yodado proporciona un aumento en la resistencia a la tracción, en la tenacidad a la fractura y en la ductilidad con ...
M. P. Ginebra +6 more
doaj +1 more source
A Novel Spatial Feature for the Identification of Motor Tasks Using High-Density Electromyography
Sensors, 2017 Estimation of neuromuscular intention using electromyography (EMG) and pattern recognition is still an open problem. One of the reasons is that the pattern-recognition approach is greatly influenced by temporal changes in electromyograms caused by the ...
Mislav Jordanić +4 more
doaj +1 more source
Molecular and functional characterization of an evolutionarily conserved CREB-binding protein in the Lymnaea CNS [PDF]
, 2022 In eukaryotes, CREB-binding protein (CBP), a coactivator of CREB, functions both as a platform for recruiting other components of the transcriptional machinery and as a histone acetyltransferase (HAT) that alters chromatin structure. We previously showed
Kemenes, I. +14 more
core +1 more source