Results 151 to 160 of about 73,335 (261)
Amygdala-hippocampus circuit regulates stress coping via mGluR5-dependent BDNF signaling. [PDF]
Kim TE, Choi TY, Koo JW, Kim J.
europepmc +1 more source
Embryonic Hormetic Priming Modulates Later‐Life Thermal Tolerance
This study investigates how early‐life thermal environments affect later thermal tolerance in the black‐lip pearl oyster, Pinctada margaritifera. Developmental thermal priming had contrasting, family‐specific effects on thermal tolerance, with conserved stress‐response pathways but evidence of priming‐induced regulatory network reorganization.
K. Lugue +7 more
wiley +1 more source
Astrocytic CREB regulates transcriptomic, neuronal, and behavioral responses to cocaine. [PDF]
Holt LM +20 more
europepmc +1 more source
This study highlights the memory‐enhancing effects of walnuts, almonds, and Torreya, with walnuts showing the strongest potential to improve cognitive function and delay brain aging. ABSTRACT This study explored the memory‐enhancing potential of seven commercially available nuts through nutritional profiling, metabolomics, network pharmacology, and ...
Jiamin Chen +10 more
wiley +1 more source
Shikonin improves intestinal barrier function through modulation of GPX4 expression in intestinal epithelial cells. [PDF]
Yang F +6 more
europepmc +1 more source
‐Pi infusion significantly improved locomotor activity and exploratory behavior in aging mice; its bioactive compounds may have direct effects on behavior, which may be accompanied by a putative indirect effect involving the gut microbiota. ‐Pi infusion consumption restored commensal Bacilli levels and caused a significant decrease in Clostridia levels
Yulia Kroupitski +7 more
wiley +1 more source
Prefrontal TRPM8 Receptor Modulates Epileptic Seizures via PKA/CREB Signaling Pathway in Mice. [PDF]
Huang JZ +6 more
europepmc +1 more source
The Mediterranean diet interacts with genetic and epigenetic backgrounds to modulate nutrigenomic mechanisms, including DNA methylation, histone modification and microRNA regulation. These molecular effects reduce inflammation and oxidative stress, enhance nitric oxide bioavailability and lipid metabolism and translate into improved cardiometabolic ...
Karina Ramírez‐Alarcón +16 more
wiley +1 more source
Exercise and dietary polyphenols enhance hippocampal plasticity and cognitive function via complementary molecular mechanisms. Central pathways include BDNF signaling, inflammation control, and mitochondrial regulation. Although synergy is mainly supported by preclinical data, lifestyle‐based strategies show promise for brain health maintenance ...
Zhenyi Zhao, Sima‐sadat Sabihi
wiley +1 more source

