Disordered activation domains enhance DNA target search rate of a bZIP transcription factor
Gaudez J, Shammas SL.
europepmc +1 more source
Isoquercitrin induces melanogenesis in B16F10 melanoma cells and zebrafish via the p38 and PKA/CREB signaling pathways: an experimental study. [PDF]
Lee JH, Ko YS, Eom YS, Kim SJ.
europepmc +1 more source
Innate Immune Tolerance Regulates Microglia Response to Aβ Oligomers
Microglia are the primary innate immune cells residing in the brain parenchyma, and their activation in Alzheimer's disease (AD) results in increased neuroinflammation. The development of innate immune memory in response to various stimuli is a crucial mechanism that allows microglia to tailor their responses to future inflammatory challenges.
Rafaela Rodrigues Valerio +9 more
wiley +1 more source
Role of the Transcription Factor CREB in Ethanol-Induced Endoplasmic Reticulum Stress and Apoptosis in PC12 Cells. [PDF]
Németh M +7 more
europepmc +1 more source
Neurons in a Dish: A Review of In Vitro Cell Models for Studying Neurogenesis
Different in vitro cell models are valuable to study the different steps of neurogenesis, from the proliferation of neural stem and progenitor cells to the maturation of neurons. Pluripotent stem cells (including embryonic stem cells and induced pluripotent stem cells), immortalized human neuroblastoma cell lines (SH‐SY5Y, IMR‐32), and primary brain ...
Mariana Vassal +3 more
wiley +1 more source
Modulating miRNA-367-3p Expression by Kaempferol Alleviates Experimental Autoimmune Encephalomyelitis: Targeting Fpn1-Dependent Ferroptosis and cAMP/CREB/CNTF Signaling. [PDF]
El-Gohary RM +10 more
europepmc +1 more source
Depression adversely impacts daily life, with age‐related neurodegeneration being a significant contributing factor. Neurodegenerative alterations, often accelerated by oxidative stress, underlie depressive progression in advanced age. Our previous research has reported that Alternanthera philoxeroides (Mart.) Griseb (AP) exhibits promising antioxidant
Possatorn Aon-im +7 more
wiley +1 more source
FBP1 promotes ABCG2-mediated uric acid excretion through activation of the PI3K/AKT/CREB signaling pathway. [PDF]
Bai Q +7 more
europepmc +1 more source
Editorial: Standardization and Biological Properties of Functional Herbal Food 2024
Numerous medical and food dual‐purpose herbs have been used for thousands of years and are still gaining influence in our daily lives. However, there are still two major questions, including chemical standardization and efficacy of these herbs, remaining to be addressed.
Jianping Chen +4 more
wiley +1 more source

