Results 241 to 250 of about 87,086 (298)

Lactate metabolism and lactylation in female reproductive diseases: From metabolic rewiring to biomarkers and translational therapeutics

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
1. Lactate‐derived histone lactylation links glycolytic reprogramming to epigenetic regulation in female reproductive diseases. 2. In endometriosis, lactylation may promote inflammatory remodelling, immune dysregulation and ferroptosis resistance. 3. In PCOS, lactylation connects metabolic disturbance to granulosa‐cell dysfunction and hyperandrogenism.
Jiajun Qiao, Yue Xiao, Yi Cheng, Weihai Xu, Jing Shu, Shishi Li   +5 more
wiley   +1 more source

Intracranial mesenchymal tumor, FET::CREB fusion-positive: An integrative analysis of 81 cases. [PDF]

Neuro Oncol
Rajan S, Chung HJ, Wu Z, Singh O, Dazelle K, Abdullaev Z, Tyagi M, Ferrone CK, Raffeld M, Lee I, Gagan J, Chen J, Cathcart S, Giannini C, Nguyen A, Gokden M, Perry A, Fernandes IL, Putnam AR, Kurek K, Green RM, Eberhart C, Lucas CH, Gonzalez-Gomez I, Lopez GY, Jones K, Prayson R, Yeaney G, Dermawan JKT, Chkheidze R, Appin C, Uhlmann EJ, Taliansky A, Blessing M, Mohila C, Cotter J, Deisch J, Andreiuolo F, Crawford JR, Mount C, Stemmer-Rachamimov AO, Lakis NS, Schmidt R, Chacko G, Newbury R, Neill S, Morales B, Fecher R, Sloan EA, Solomon DA, Nasrallah M, Quezado M, Fonseca A, Aldape K.   +53 more
europepmc   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

Fluoxetine Repurposing Mitigates Alzheimer's Disease Pathology via the GSK3β-CREB-ADAM10 Axis. [PDF]

Int J Mol Sci
Lee SH, Son Y, Jang H, Kim HY, Kim KS, Lee HS, Lee HJ.   +6 more
europepmc   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, Volume 3, Issue 2, Page 237-251, June 2026.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Neuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafish. [PDF]

Sci Adv
Mackensen T, Iñiguez LP, Soares Mullen T, Rodriguez-Marin C, Kroll F, Zuccarini G, Fernandez-Albert J, Sancho-Vila L, Permanyer J, Bianco IH, Orger M, Rihel J, Irimia M.   +12 more
europepmc   +1 more source

Dopamine D2 Receptors, D1/D2 Receptor Heteromers and CaMKII Signaling in the Neurobiology of Drug Addiction. [PDF]

Mol Neurobiol
Jia W, He X, Cheng A, He Y, Zhao F, Fukunaga K, Zhao W.   +6 more
europepmc   +1 more source

A Potential Functional Food-Based Neuroprotective Strategy Using Mulberry Leaf Extract and Trolox Against H₂O₂-Induced Oxidative Stress in SH-SY5Y Cells. [PDF]

Foods
Mairuae N, Phanphak J, Thipboonchoo N, Wilaisit P, Butsamongkon P, Chotritthirong Y, Kaewbutra S, Loiklung C, Palachai N.   +8 more
europepmc   +1 more source

Effect of lithium on the CREB interacting cofactors CBP (CREB binding protein) and TORC (transducer of regulated creb)

, 2018
Boer, U., Krause, D., Knepel, Willhart
openaire   +1 more source

CREB dimerization is crucial for the interaction with TORC (transducer of regulated CREB)

, 2018
Heinrich, A., Boeer, Ulrike, Knepel, Willhart   +2 more
openaire   +1 more source