Results 251 to 260 of about 87,086 (298)
The expanding landscape of the glucagon signaling network: mechanisms and outcomes.
EndocrinologyFoollee A, Wu Y, Rusu PM, Rose AJ.
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CREB − a real culprit in oncogenesis [PDF]
FEBS Journal, 2007 The cAMP response element‐binding protein (CREB) is a stimulus‐induced transcription factor that responds rapidly to phosphorylation and/or coactivator activation. Regulated activation of CREB has a significant impact on cellular growth, proliferation and survival.
Dong-Yan Jin
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Frontiers in Bioscience, 2004
Programmed cell death (PCD) is major concept in neurobiology and transcription factors are pivotal in switching on the nerve cell death program. More recently, the transcriptional control of programmed cell life (PCL) is beginning to be understood. This work began in studies of the activation of the CREB transcription factor in stroke models where it ...
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Programmed cell death (PCD) is major concept in neurobiology and transcription factors are pivotal in switching on the nerve cell death program. More recently, the transcriptional control of programmed cell life (PCL) is beginning to be understood. This work began in studies of the activation of the CREB transcription factor in stroke models where it ...
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Neurobiology of Disease, 2008 Our previous research indicates that the extracellular signal-regulated kinase (ERK)-cyclic AMP-responsive-element-binding protein (CREB) signal system may be involved in the molecular mechanism of depression.
Xiaoli Qi, Wenjuan Lin, Junfa Li
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CREB-1 and CREB-2 immunoreactivity in the rat brain
Brain Research, 1996This study is focused to learn about the cellular localization of transcription factors binding to the cAMP response element-CREBs-in the brain of normal rats and in animals subjected to excitotoxic cell damage. For this purpose, CREB-1 and CREB-2 immunoreactivity is examined in the developing and adult rat brain under physiological conditions, and ...
I, Ferrer +6 more
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Trends in Neurosciences, 2005
The transcription factor CREB is best known for its involvement in learning and memory. However, emerging evidence suggests that CREB activity has very different roles--sometimes beneficial, sometimes detrimental--depending on the brain region involved.
William A, Carlezon +2 more
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The transcription factor CREB is best known for its involvement in learning and memory. However, emerging evidence suggests that CREB activity has very different roles--sometimes beneficial, sometimes detrimental--depending on the brain region involved.
William A, Carlezon +2 more
openaire +2 more sources
CREB-Mediated Transcriptional Control
Critical Reviews in Eukaryotic Gene Expression, 1999cAMP-response-element-binding protein, CREB, is a 43-kDa leucine zipper transcription factor identified and cloned via the study of cAMP-regulated genes. In the last decade, numerous studies have contributed much to our understanding of CREB structure, function, and CREB-mediated transcription.
Ourania M Andrisani
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2002
Abstract In technical terms, which will be explained below, CREB, CAMP-response element-binding protein, is a protein that modulates the transcription of genes with CAMP-response elements in their promoters. CREB is one of the most commonly used acronyms in neurobiology these days, and also one of the few words in the jargon of molecular
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Abstract In technical terms, which will be explained below, CREB, CAMP-response element-binding protein, is a protein that modulates the transcription of genes with CAMP-response elements in their promoters. CREB is one of the most commonly used acronyms in neurobiology these days, and also one of the few words in the jargon of molecular
openaire +1 more source
Cellular and Molecular Life Sciences (CMLS), 1999
The prevailing hypothesis for the formation of long-term memory (LTM) is that introduction of a memory item alters the pattern of existing neuronal connectivity to form a neuronal network that will subserve the information for long-term storage. Modulation of synaptic efficacy is induced by changes in synaptic transmission within selected synapses or ...
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The prevailing hypothesis for the formation of long-term memory (LTM) is that introduction of a memory item alters the pattern of existing neuronal connectivity to form a neuronal network that will subserve the information for long-term storage. Modulation of synaptic efficacy is induced by changes in synaptic transmission within selected synapses or ...
openaire +2 more sources