Results 71 to 80 of about 91,942 (288)

Knock-in Luciferase Reporter Mice for In Vivo Monitoring of CREB Activity. [PDF]

PLoS ONE, 2016
The cAMP response element binding protein (CREB) is induced during fasting in the liver, where it stimulates transcription of rate-limiting gluconeogenic genes to maintain metabolic homeostasis.
Dmitry Akhmedov, Kavitha Rajendran, Maria G Mendoza-Rodriguez, Rebecca Berdeaux   +3 more
doaj   +1 more source

Tailor-made memory: natural differences in associative olfactory learning in two closely related wasp species [PDF]

, 2009
Learning and memory formation are often seen as traits that are purely beneficial, but they are associated with metabolic costs as well. Since costs and gains of learning and memory are expected to vary between species, the ease and speed with which ...
Berg, M., van den, van den Berg, M.
core  

Glucose and Glutamine Deprivation Promotes Breast Cancer Lung Metastasis via BRD4‐Dependent Enhancer Activation

Advanced Science, EarlyView.
To model a nutrient‐restricted tumor microenvironment, breast cancer cells were adapted to low glucose and glutamine levels. In the adapted cells, BRD4‐driven enhancer activation increases pro‐invasive EDN1 expression, facilitated by ATF3/c‐JUN and reinforced by enhancer RNA.
Poshan Yugal Bhattarai, Arathy Vasukutty, Yujin Na, Sung‐Chul Lim, Hong Seok Choi   +4 more
wiley   +1 more source

Pulsed Electromagnetic Fields: A Novel Attractive Therapeutic Opportunity for Neuroprotection After Acute Cerebral Ischemia

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone, Simona Salati, Fabrizio Vincenzi, Micaela Liberti, Giorgio Aicardi, Francesca Apollonio, Katia Varani, Ruggero Cadossi, Vincenzo Di Lazzaro   +8 more
wiley   +1 more source

Pentylenetetrazol and Morphine Interaction in a State-dependent Memory Model: Role of CREB Signaling

Basic and Clinical Neuroscience, 2020
Introduction: State-dependent (STD) memory is a process, in which the learned information can be optimally retrieved only when the subject is in the state similar to the encoding phase. This phenomenon has been widely studied with morphine.
Marziyeh Tavassoli, Abolfazl Ardjmand
doaj  

Evaluación de la Función Neuromuscular del Antebrazo durante contracciones isométricas mediante Electromiografía de Superficie Multicanal

Revista Iberoamericana de Automática e Informática Industrial RIAI, 2011
Resumen: Desarrollo de un protocolo experimental con ejercicios de flexión isométrica de los dedos y muñeca asociado a lesiones de esfuerzo repetitivo, y validación de la electromiografía de superficie multicanal como técnica no invasiva en la ...
Mónica Rojas-Martínez, Michelle García, Joan Francesc Alonso, Jesús Marín, Miguel Ángel Mañanas   +4 more
doaj   +1 more source

Cyclic mechanical strain causes cAMP-response element binding protein activation by different pathways in cardiac fibroblasts

Heart International, 2010
The transcription factor cAMP-response element binding protein (CREB) mediates the mechanical strain-induced gene expression in the heart. This study investigated which signaling pathways are involved in the strain-induced CREB activation using cultured ...
Britta Husse, Gerrit Isenberg
doaj   +1 more source

Marine‐Derived Type I Collagen From Scyliorhinus canicula: Extraction, Characterization, and Biomedical Applications

Journal of Applied Polymer Science, EarlyView.
Marine‐derived type I collagen is extracted from Scyliorhinus canicula skin and characterized by physicochemical and morphological analyses. The collagen exhibits excellent biocompatibility, promotes wound healing, reduces inflammatory mediators, and inhibits melanogenesis.
Marwa Rejeb, Aida Lahmar, Arem Selmi, Tahsine Kosksi, Nawres Debbabi, Ghania Hamdi‐Degobert, Leila Chekir‐Ghedira   +6 more
wiley   +1 more source

Ligustroside derived from Ligustrum japonicum inhibits melanogenesis via blocking the MAPK and PKA/CREB signaling pathways

Asian Pacific Journal of Tropical Biomedicine
Objective: To investigate the anti-melanogenic potential of ligustroside isolated from Ligustrum japonicum. Methods: The cytotoxicity of ligustroside was tested via MTT assay.
Xian-Rong Zhou, Fatih Karadeniz, Jung Hwan Oh, Youngwan Seo, Chang-Suk Kong   +4 more
doaj   +1 more source

Increased abscess formation and defective chemokine regulation in CREB transgenic mice.

PLoS ONE, 2013
Cyclic AMP-response element-binding protein (CREB) is a transcription factor implicated in growth factor-dependent cell proliferation and survival, glucose homeostasis, spermatogenesis, circadian rhythms, and synaptic plasticity associated with memory ...
Andy Y Wen, Elliot M Landaw, Rachel Ochoa, Michelle Cho, Alex Chao, Gregory Lawson, Kathleen M Sakamoto   +6 more
doaj   +1 more source