Comparative speed of kill of induced Ixodes scapularis infestations following treatment of dogs with endectocides containing either sarolaner (Simparica Trio™), afoxolaner (NexGard® PLUS), or lotilaner (Credelio Quattro™) [PDF]
Parasites & VectorsBackground Ixodes scapularis is a consequential tick species in North America that can transmit multiple pathogens of canine and public health significance. Acaricidal speed is critical for reducing the risk of pathogen transmission.
Kathryn E. Reif +13 more
doaj +3 more sources
Safety of oral afoxolaner formulated with or without milbemycin oxime in homozygous MDR1-deficient collie dogs. [PDF]
J Vet Pharmacol Ther, 2022 Abstract Afoxolaner, an insecticide and acaricide compound of the isoxazoline class, is available for dogs as an oral ectoparasiticide medicine (NexGard®) and as an oral endectoparasiticide medicine in combination with milbemycin oxime (MO), a macrocyclic lactone (NexGard® Spectra).
Drag M, Tielemans E, Mitchell E.
europepmc +2 more sources
Efficacy of lotilaner (Credelio™ chewable tablets) for preventing Babesia canis transmission to dogs by infected Dermacentor reticulatus ticks [PDF]
Parasites & VectorsBackground Canine babesiosis is a clinically significant tick-borne disease, caused by different Babesia species. Babesia canis, one of the most important and widespread species in Europe, is transmitted by Dermacentor reticulatus ticks and can cause ...
Katrin Deuster +7 more
doaj +2 more sources
First Report of Bronchial Oestriasis in a Domestic Dog. [PDF]
Vet Med SciOestrus ovis bronchial myasis is described in a dog for the first time. Bronchoscopy proved essential for larval visualization and removal. Isoxazoline compounds should be considered both as a treatment and as a preventive option. ABSTRACT This study reports the first case of bronchial myiasis in a dog caused by Oestrus ovis, a parasite known to infest
Dini FM +4 more
europepmc +2 more sources
Survey of canine use and safety of isoxazoline parasiticides. [PDF]
Vet Med Sci, 2020 A veterinarian and pet owner survey (Project Jake) examined the use and safety of isoxazoline parasiticides given to dogs during August 1‐31, 2018 from 2751 survey responses. When any preventive treatment was given, AE were reported for 66.6% of respondents, with no apparent AE noted for 36.1%.
Palmieri V +7 more
europepmc +2 more sources
Safety evaluation of lotilaner in dogs after oral administration as flavoured chewable tablets (Credelio™) [PDF]
Parasites & Vectors, 2017 Background Lotilaner (Credelio™, Elanco) is a novel isoxazoline that provides rapid speed of flea and tick knockdown which is sustained for at least 1 month following oral administration to dogs.
Emmanuelle A. Kuntz +1 more
doaj +3 more sources
A randomized, controlled study to assess the efficacy and safety of lotilaner (Credelio™) in controlling ticks in client-owned dogs in Europe [PDF]
Parasites & Vectors, 2017 Background Oral administration of lotilaner flavoured chewable tablets (Credelio™, Elanco) to dogs has been shown to provide a rapid onset of killing activity of infesting ticks, with sustained efficacy for at least 35 days.
Daniela Cavalleri +4 more
doaj +3 more sources
Efficacy of lotilaner against myiasis caused by Cochliomyia hominivorax (Diptera: Calliphoridae) in naturally infested dogs [PDF]
Parasites & Vectors, 2023 Background The New World screwworm fly, Cochliomyia hominivorax, is widely distributed across South America. This parasitic insect is a significant cause of primary myiasis in animals, including dogs.
Tássia Lopes do Vale +9 more
doaj +2 more sources
A randomized, controlled field study to assess the efficacy and safety of lotilaner (Credelio™) in controlling ticks in client-owned cats in Europe [PDF]
Parasites & Vectors, 2018 Background There is a continuing need for novel approaches to tick infestations treatment and control in cats. Lotilaner, an isoxazoline with rapid onset of action, has proven its efficacy against ticks in laboratory studies.
Daniela Cavalleri +3 more
doaj +6 more sources
Laboratory evaluations of the immediate and sustained efficacy of lotilaner (Credelio™) against four common species of ticks affecting dogs in North America [PDF]
Parasites & Vectors, 2017 Background Effective control of tick infestations on dogs is important to reduce the risk of transmission of bacterial, viral, and protozoal pathogens.
Martin Murphy +9 more
doaj +3 more sources