Laboratory evaluations of the immediate and sustained effectiveness of lotilaner (Credelio™) against three common species of ticks affecting dogs in Europe [PDF]
Parasites & Vectors, 2017 Background There is a continuing need for novel approaches to tick control in dogs. One such approach lies in the ability of lotilaner (Credelio™), an isoxazoline with a rapid onset of action, to provide sustained efficacy against ticks. Two studies were
Daniela Cavalleri +5 more
doaj +3 more sources
Assessment of the onset of lotilaner (Credelio™) speed of kill of fleas on dogs [PDF]
Parasites & Vectors, 2017 Background Lotilaner (Credelio™) is the newest member of the novel isoxazoline chemical class to be developed to treat canine ectoparasitism. Administered orally, lotilaner is rapidly absorbed with peak blood levels occurring within 2 h post-treatment. A
Daniela Cavalleri +4 more
doaj +3 more sources
Assessment of the speed of flea kill of lotilaner (Credelio™) throughout the month following oral administration to dogs [PDF]
Parasites & Vectors, 2017 Background Lotilaner (Credelio™, Elanco), a novel isoxazoline, is a systemic insecticide and acaricide that is rapidly absorbed following oral administration to dogs and has a half-life of 30 days.
Daniela Cavalleri +4 more
doaj +3 more sources
Menrath ulcers in cats: four cases (2014-2023). [PDF]
J Small Anim PractObjectives To report the clinical presentation, treatment and outcomes of four cats diagnosed with Menrath ulcers causing significant oral haemorrhage. Materials and Methods For all cats, data on signalment, history, physical examination, treatment and outcomes were collected by reviewing medical records.
Whybrow K, Hernon T, Pilot M.
europepmc +2 more sources
Laboratory evaluation of the efficacy of lotilaner (Credelio™) against Amblyomma cajennense (sensu lato) infestations of dogs [PDF]
Parasites & Vectors, 2018 Background The ixodid tick Amblyomma cajennense (sensu lato) complex, widespread throughout South and Central America, is also present in Mexico, Texas and Florida.
Pedro Veloso Facury Lasmar +7 more
doaj +3 more sources
A randomised, blinded, controlled field study to assess the efficacy and safety of lotilaner tablets (Credelio™) in controlling fleas in client-owned dogs in European countries [PDF]
Parasites & Vectors, 2017 Background Lotilaner is a novel isoxazoline developed for oral administration to dogs. In laboratory studies, lotilaner was shown to be safe and to produce a rapid flea and tick knockdown, with a sustained speed of kill for at least a month post ...
Daniela Cavalleri +4 more
doaj +3 more sources
Efficacy of lotilaner (Credelio™), a novel oral isoxazoline against naturally occurring mange mite infestations in dogs caused by Demodex spp. [PDF]
Parasites & Vectors, 2017 Background The oral systemic efficacy of lotilaner (Credelio™, Elanco) was evaluated against Demodex spp. in naturally infested dogs with generalized demodicosis.
Daniel E. Snyder +2 more
doaj +3 more sources
Two randomized, controlled studies to assess the efficacy and safety of lotilaner (Credelio™) in preventing Dermacentor reticulatus transmission of Babesia canis to dogs [PDF]
Parasites & Vectors, 2017 Background Dogs worldwide are at risk of Babesia spp. infections. Preventive efficacy of lotilaner tablets (Credelio™, Elanco) against Babesia canis was evaluated in two studies.
Daniela Cavalleri +4 more
doaj +3 more sources
A randomized, controlled field study to assess the efficacy and safety of lotilaner (Credelio™) in controlling fleas in client-owned cats in Europe [PDF]
Parasites & Vectors, 2018 Background Lotilaner is a new isoxazoline developed as an oral ectoparasiticide for cats and dogs. Its safety, rapid killing onset of action and sustained speed of fleas and ticks kill for a minimum of one month after administration, were demonstrated in
Daniela Cavalleri +3 more
doaj +2 more sources
The novel isoxazoline ectoparasiticide lotilaner (Credelio™): a non-competitive antagonist specific to invertebrates γ-aminobutyric acid-gated chloride channels (GABACls) [PDF]
Parasites & Vectors, 2017 Background The isoxazolines are a novel class of parasiticides that are potent inhibitors of γ-aminobutyric acid (GABA)-gated chloride channels (GABACls) and, to a lesser extent, of inhibitory glutamate-gated chloride channels (GluCls).
Lucien Rufener +3 more
doaj +3 more sources