Results 41 to 50 of about 99,751 (297)

In Situ 3D-µ-Tomography on Particle-Reinforced Light Metal Matrix Composite Materials under Creep Conditions

Metals, 2020
In transportation light metal matrix composites (L-MMCs) are used increasingly due to their improved creep resistance even at higher application temperatures. Therefore, the creep behavior and failure mechanisms of creep loaded particle reinforced L-MMCs
Bettina Camin, Lennart Hansen
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Viscoelastic plastic creep constitutive model based on energy conservation law and strain energy theory

Scientific Reports
On the basis of the law of conservation of energy, the three stages of rock creep are analyzed. The reasons for the difficulty in studying the accelerated creep stage of rocks using the traditional creep model are expounded.
Di Zhou, Xiangjin Tian, Shuguang Zhang, Wang Zeng, Minye Zhang, Yanchao Feng, Wenbo Liu, Xiang Huang, Mingzhuo Fan, Ye Sun   +9 more
doaj   +1 more source

Creep properties and resistivity-ultrasonic-AE responses of cemented gangue backfill column under high-stress area

International Journal of Mining Science and Technology, 2021
To investigate the creep and instability properties of a cemented gangue backfill column under a high-stress area, the uniaxial compression creep tests were conducted by single-step and multi-step loading of prismatic samples made of cemented gangue ...
Hongyu Ran, Yuxia Guo, Guorui Feng, Tingye Qi, Xianjie Du   +4 more
doaj  

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

From information creep to indication creep

The Journal of Thoracic and Cardiovascular Surgery
No abstract ...
Amedeo Anselmi, Sylvain Beurtheret, Fabio Barili, Ovidio A García-Villarreal   +3 more
openaire   +2 more sources

Creep damage evolution and instability induction mechanism of rock under impact disturbance

Meitan xuebao
In order to study the creep damage mechanism of composite coal rock mass under impact disturbance, based on the creep equation model under complex stress and considering the heterogeneity of coal and rock materials, a creep damage constitutive model ...
Dongliang JI, Hui CHENG, Hongbao ZHAO, Yuezhuoer GUAN, Xinqiang GAO, Mingjiu XUE, Guozheng SHI, Yunbo JIA   +7 more
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

The Establishment of a Rock Creep Model by Using Creep Bodies via an Improved Gene Expression Programming Algorithm

Applied Sciences
Rock creep commonly appears in rock mass engineering, and it should be paid appropriate attention. In this paper, studies on creep constitutive models of rocks were reviewed, and it was found that the types of creep constitutive models can generally be ...
Pingyang Fan, Junhua Chen, Chuankun Qiu, Junwen Chen, Shan Gao, Jiqing Hou, Min Wang   +6 more
doaj   +1 more source