Results 121 to 130 of about 29,556 (312)

Creep of Sn-0.3Ag-0.7Cu solder in electronic packaging: Experiment and simulation

Journal of Materials Research and Technology
In contemporary society, the growing reliance on electronic devices has necessitated the phasing out of traditional Sn–Pb solder due to its health hazards, prompting a transition to environmentally friendly, lead-free alternatives.This study aims to ...
Yuezong Zheng, Junchen Liu, Hongchao Ji, Xiaomin Huang, Wenchao Xiao, Abdullah Aziz Saad   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

History-sensitive accumulation rules for life-time prediction under variable loading

, 2011
This is the post-print version of the article. The official published version can be obtained from the link below - Copyright @ 2011 SpringerA general form of temporal strength conditions under variable creep loading is employed to formulate several new ...
Mikhailov, SE, S. E. Mikhailov, I. V. Namestnikova, Namestnikova, IV   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Development of Advanced Creep Damage Constitutive Equations for Low CR Alloy Under Long-Term Service

Low Cr alloys are mostly utilized in structural components such as steam pipes, turbine generators and reactor pumps operating at high temperatures from 400℃ to 700℃ in nuclear power plants.
Xu, Qihua
core  

CREEP Coefficient and Specific Creep of Engineered Cementitious Composite -Bendable Concrete

Civil and Environmental Engineering
Creep is a complex behavior of concrete since it induces different stages of response under loading and unloading with time. It represents the time-dependent strain as a result of a constant sustained load applied with time.
Al-Mulla Ikram Faraoun, Al-Ameeri Abbas Salim, Al-Attar Tareq Salih   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Creep behavior of rock [PDF]

, 2012
Mining activities of minerals play a very important role on the health and wealth of any nation. Though technology has reduced the adverse effects to a great extent, it is still experiencing unpredictable behavior of rocks.
Bhoi, Manas Ranjan
core  

Research on the Short-Term Compressive Creep Behavior of the Bamboo Scrimber Based on Different Zener Models

Applied Sciences
For the gluing process of natural fiber-reinforced composite materials like bamboo scrimber, an obvious creep behavior can be found during the working stage, which must be seriously considered in safety and reliability design.
Shuqin Wang, Songsong Sun, Xiaolin Gong, Jiahong Fu   +3 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source