Results 101 to 110 of about 146,033 (308)
A creep model for metallic composites based on matrix testing: Application to Kanthal composites [PDF]
An anisotropic creep model is formulated for metallic composites with strong fibers and low to moderate fiber volume percent (less than 40 percent).
Arnold, S. M. +3 more
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Mechanical behavior of polycrystalline non-metallics at elevated temperature Progress report, Apr. 1 - Sep. 30, 1965 [PDF]
Creep behavior of polycrystalline aluminum oxide and sodium chloride at high ...
Burke, P., Sherby, O. D.
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Interface Motion in Disordered Ferromagnets
, 2002 We consider numerically the depinning transition in the random-field Ising model. Our analysis reveals that the three and four dimensional model displays a simple scaling behavior whereas the five dimensional scaling behavior is affected by logarithmic ...
Lubeck, S., Roters, L., Usadel, K. D.
core +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Long-time creep behavior of the niobium alloy C-103 [PDF]
The creep behavior of C-103 was studied as a function of stress, temperature, and grain size for test times to 19000 hr. Over the temperature range 827 to 1204 C and the stress range 6.89 to 138 MPa, only tertiary (accelerating) creep was observed.
Klopp, W. D., Titran, R. H.
core +1 more source
Correlations Between Metallurgical Characterization Studies, Exploratory Mechanical Tests, and Continuum Mechanics Approaches to Constitutive Equations [PDF]
, 1983 Austenitic stainless steels, such as types 316 and 304, are widely used as pressure vessel materials in the temperature range of 425 to 650 C. Stainless steel specimens were tested to rupture at two different stress levels sigma and sigma 2 sigma 1 sigma
Moteff, J. +2 more
core +1 more source
Creep crack growth behavior of P91 steel weldments
Thermal Science, 2019 The steels operating at elevated temperatures are well known to be exposed to premature failure due to cracking caused by constant thermal stress, i.e. secondary creep process. Therefore, creep crack growth (CCG) tests were carried out on compact tension (CT) specimens machined from P91 weld joint at 600°C to determine its behaviour in realistic ...
Swei, Mohamed +6 more
openaire +4 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source