Results 91 to 100 of about 29,556 (312)

Creep Properties of Walikukun (Schouthenia ovata) Timber Beams

Civil Engineering Dimension, 2016
This study presents an evaluation of creep constants of Walikukun (Schoutheniaovata) timber beams when rheological model of four solid elements, which is obtained byassembling Kelvin and Maxwell bodies in parallel configuration, was adopted.
Ali Awaludin, Ngudiyono Ngudiyono, Achmad Basuki   +2 more
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Safe structural design for fatigue and creep using cyclic yield strength

, 2014
This study proposes cyclic yield strength (CYS, σ_cy) as a potential characteristic of safe design for structures operating under fatigue and creep conditions.
Gorash, Yevgen, Mackenzie, Donald
core  

Atomic-scale Simulation Study of Creep Behavior in Nanocrystalline Mo

Yuanzineng kexue jishu
Molybdenum (Mo) alloys are widely employed in high-temperature environments, such as advanced nuclear systems, due to their excellent properties, including high melting point and thermal conductivity. However, Mo alloys suffer from poor ductility at room
NI Weixuan, JIA Lixia, DOU Yankun, HE Xinfu, CAO Jinli, WANG Dongjie, YANG Wen
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Plastic deformation of dense nanocrystalline yttrium oxide at elevated temperatures [PDF]

, 2012
Nanocrystalline yttrium oxide, Y2O3 with 110 nm average grain size was plastically deformed between 800 ◦C and 1100 ◦C by compression at different strain rates and by creep at different stresses. The onset temperature for plasticity was at 1000 ◦C. Yield
Estournès, Claude, Gallardo-López, Angela, Domínguez-Rodríguez, Arturo, Chaim, Rachman, Marder, Rachel   +4 more
core   +1 more source

Anisotropic time-dependent behaviors of shale under direct shearing and associated empirical creep models

Journal of Rock Mechanics and Geotechnical Engineering
Understanding the anisotropic creep behaviors of shale under direct shearing is a challenging issue. In this context, we conducted shear-creep and steady-creep tests on shale with five bedding orientations (i.e.
Yachen Xie, Michael Z. Hou, Hejuan Liu, Cunbao Li   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Novel direct method on the life prediction of component under high temperature-creep fatigue conditions

, 2013
This paper presents a novel direct method, within the Linear Matching Method (LMM) framework, for the direct evaluation of steady state cyclic behaviour of structures subjected to high temperature – creep fatigue conditions.
Chen, Haofeng, Gorash, Yevgen
core  

Experimental Research and Numerical Simulation of Post-Crack Creep Behavior of SFRC Loaded in TensionMechanics and Physics of Creep, Shrinkage, and Durability of Concrete

, 2013
This paper mainly studies uniaxial tensile creep behavior of pre-cracked steel fiber reinforced concrete (SFRC). A series of uniaxial tensile creep tests were carried out on SFRC cylinder specimens which were pre-cracked at 0.2mm.
Guanyu Zhao, Lucie Vandewalle, Marco di Prisco, DI PRISCO, MARCO   +3 more
core   +1 more source