Results 41 to 50 of about 21,077 (297)

Anisotropic creep model for soft soils

, 2008
In this paper a new anisotropic model for time-dependent behaviour of soft soils is presented. The formulation is based on a previously developed isotropic creep model, assuming rotated Modified Cam Clay ellipses as contours of volumetric creep strain ...
Leoni, Martino, EC MRTN-CT-2004–512120 (Funder), , EC MRTN-CT-2004–512120 (Funder), , Academy of Finland Grant 210744 (Funder), Academy of Finland Grant 210744 (Funder), , University of Stuttgart, Vermeer, Pieter, University of Stuttgart, University of Strathclyde, , University of Strathclyde, Karstunen, Minna   +10 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Influence of geometry on creep and moisture movement of clay, calcium silicate and concrete masonry [PDF]

, 1989
This investigation involved creep and moisture movement measurements for about six months on 13-course clay (Engineering class B) and calcium silicate brickwork, and 5-course concrete blockwork, consecutively.
Abdulla, Che Sobry
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Creep characteristics and constitutive model construction of offshore soft soils

Journal of Traffic and Transportation Engineering (English ed. Online)
The main objective of this study was to investigate creep characteristics and construct a suitable constitutive model for soft soils in offshore areas. Soft soil samples were obtained to evaluate the physical and mechanical properties.
Hainian Wang, Wenhua Zheng, Linlong Shao, Ponan Feng, Tongtong Wan, Heyang Ding   +5 more
doaj   +1 more source

Increasing weaning age of piglets from 4 to 7 weeks reduces stress, increases post-weaning feed intake but does not improve intestinal functionality

, 2010
This study tested the hypothesis that late weaning and the availability of creep feed during the suckling period compared with early weaning, improves feed intake, decreases stress and improves the integrity of the intestinal tract.
Hoogendoorn, A., Dekker, R.A., Meulen, J., van der, Koopmans, S.J.   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Creep constitutive model of strain energy density considering the whole process of creep deformation.

PLoS ONE
Aiming at the problem that the traditional creep model is difficult to reflect the characteristics of accelerated creep stage of rock, the influence of stress state on accelerated creep is fully considered, and a constitutive model which can describe ...
Yuemei Li
doaj   +1 more source