Results 51 to 60 of about 15,621 (262)

Creep model of roadway surrounding rock considering hardening effect and damage effect.

PLoS ONE
The influence of confining pressure on creep characteristics was analyzed by carrying out creep tests of rocks under different confining pressures. A new creep model of roadway surrounding rock considering the combined influence of hardening effect and ...
Hongmiao Lv
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Experimental investigation of the mechanical properties of mud shale under water-bearing conditions and its applications

Scientific Reports, 2022
Mud shale, used in drilling engineering, is prone to hydration and expansion, resulting in creep deformation that leads to wellbore shrinkage and pipe sticking incidents.
Xinxin Fang, Hong Feng, Fengling Li, Hao Wang   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Insights of the asynchronous strain evolution of lean coal in uniaxial compression creep

Scientific Reports
Owing to the heterogeneity, discontinuity and complex material structure, typical coal exhibits intricate deformation characteristics during long-term creep processes.
Tingting Cai, Jia Liu, Zengchao Feng, Kai Wang, Yongxing Shen, Yulong Jiang, Bichuan Zhang   +6 more
doaj   +1 more source

Creep Characteristics of Fractured Sandstone Under the Coupling Action of Axial Compression and Hydraulic Pressure

工程科学与技术, 2021
In the construction of water conservancy, hydropower, underwater tunnels and other geotechnical engineering, rock materials with initial damage are under the coupling action of axial compression and hydraulic pressure for a long time, which seriously ...
Defeng LIU, Pengtao LIU, Zhenyue ZHANG, Yinlong XI, Xiuwei CHAI   +4 more
doaj  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Study on symmetric creep model based on creep curves and parametric sensitivity analysis

Meitan kexue jishu
In order to obtain the creep characteristics of the surrounding rock of the Dianzhong water diversion tunnel and to study the long-term stability of the surrounding rock of the tunnel, a fully automated triaxial developed by Wuhan Institute of ...
Wenbo LIU, Shuguang ZHANG, Xiang HUANG, Yipin LIU   +3 more
doaj   +1 more source