Results 71 to 80 of about 21,077 (297)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Study on symmetric creep model based on creep curves and parametric sensitivity analysis
Meitan kexue jishuIn order to obtain the creep characteristics of the surrounding rock of the Dianzhong water diversion tunnel and to study the long-term stability of the surrounding rock of the tunnel, a fully automated triaxial developed by Wuhan Institute of ...
Wenbo LIU +3 more
doaj +1 more source
, 2013 This paper presents a review of creep deformation and rupture mechanisms of low Cr-Mo alloy for the development of its creep damage constitutive equations under lower stress.
Xu, Qiang +4 more
core
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
工程科学与技术, 2021 In the construction of water conservancy, hydropower, underwater tunnels and other geotechnical engineering, rock materials with initial damage are under the coupling action of axial compression and hydraulic pressure for a long time, which seriously ...
Defeng LIU +4 more
doaj
Influence of grain size and niobium content on the creep resistance of ferritic stainless steels
, 2008 Includes abstract.Includes bibliographical references (leaves 98-102).Type 441 ferritic stainless steel is used for the production of catalytic converter housings.
Cain, Victoria
core
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
The Progressive Development and Post-failure Behaviour of Deep-seated Landslide Complexes [PDF]
, 2011 The concept of progressive shear surface development remains to be fully understood. This study aims to investigate the mechanisms of progressive shear surface development to failure, and the subsequent post-failure behaviour, of deep-seated landslide ...
CAREY, JONATHAN,MARTIN +1 more
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source