Results 91 to 100 of about 21,077 (297)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Creep properties at ambient temperature of some high strength steels.

, 1979
Ambient temperature stress relaxation and creep data are reported at various stress levels for two grades of MAR300 steel, a MAR350 steel and a type 301 stainless steel. Analysis has shown that there is a linear relationship between the logarithm of time
Barton, SG, Pollock, JTA
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Study on Creep Behavior of Wenzhou Remolded Coastal Silt Under One-Dimensional and Triaxial Tests

Buildings
This study investigates the creep behavior of remolded Wenzhou (China) coastal silt through one-dimensional (1D) and triaxial creep tests. Results show that the secondary consolidation coefficient exhibits a non-monotonic response to stress levels, while
Yi Shi, Yongwei Chen, Xiaohui Yi, Wei Qin, Zhijin Zhou, Guoxiang Peng, Kun Lou, Yuanyuan Liu   +7 more
doaj   +1 more source

Study on creep characteristics and component model of saline soil in hexi corridor. [PDF]

Sci Rep, 2023
Yu YY, Luo CL, Cui WH, Tao JY, Zhang TH.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Study on Shear Creep Characteristics of the Discontinuities with Different 3D Morphologies. [PDF]

Materials (Basel), 2023
Zhang Q, Luo Z, Chen Y, Wang Z.
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Kinetics of Mechanical Alloying, Mechanical Properties of Micro and Nanostructural Al-C Systems

High Temperature Materials and Processes, 2012
A method of mechanical alloying process is described. Carbon transformation to Al4C3 is characterized within the different heat treatment schedules and nine commercial carbon powders are tested.
Besterci Michal, Sülleiová Katarína, Velgosová Oksana   +2 more
doaj   +1 more source